Causal effects of key air pollutants and meteorology on ischemic stroke onset: A convergent cross-mapping approach
Background: Evidence suggests that environmental factors may influence the risk of ischemic stroke(IS).11 ischemic stroke(IS). Nevertheless, the majority of existing research has concentrated on correlation analysis, with only a limited number of studies employing specific methodologies to investiga...
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Elsevier
2025-02-01
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| Series: | Ecotoxicology and Environmental Safety |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651325001976 |
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| author | Cheng Zhou Haoran Li Yang Hu Bingyin Zhang Pinxian Ren Zhe Kan Xianjie Jia Jing Mi Xiaolei Guo |
| author_facet | Cheng Zhou Haoran Li Yang Hu Bingyin Zhang Pinxian Ren Zhe Kan Xianjie Jia Jing Mi Xiaolei Guo |
| author_sort | Cheng Zhou |
| collection | DOAJ |
| description | Background: Evidence suggests that environmental factors may influence the risk of ischemic stroke(IS).11 ischemic stroke(IS). Nevertheless, the majority of existing research has concentrated on correlation analysis, with only a limited number of studies employing specific methodologies to investigate the causal dynamics of this relationship with external drivers. Method: In this study, we employed an approach known as convergent cross-mapping to identify and elucidate the causal effects of significant air pollutants and meteorological factors on the pathogenesis of IS. The city of Shouguang in the Shandong Peninsula region was selected for this study, primarily because of the environmental characteristics of the region and the notable prevalence of cases during the study period. Results: Key air pollutants and several meteorological factors in the region have a causal effects on IS. A general trend can be drawn. SO222 sulfur dioxide(SO2) (ρ = 0.215, ∂=0.016), PM2.533 Particulate matter with a diameter< 2.5 μm(PM2.5) (ρ = 0.077, ∂=0.002), and PM1044 Particulate matter with a diameter< 10 μm(PM10) (ρ = 0.058, ∂=0.0014) had a positive causal effects on IS,and relative humidity (ρ = 0.050, ∂=-0.009) tended to reduce the number of IS cases. Conclusion: Through this case study, a causal network was developed with the aim of integrating the study of the interactions between variables and providing a clear model to aid the management of IS. |
| format | Article |
| id | doaj-art-7ee828b52e3642fcbca76b9a3a6efb49 |
| institution | OA Journals |
| issn | 0147-6513 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
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| series | Ecotoxicology and Environmental Safety |
| spelling | doaj-art-7ee828b52e3642fcbca76b9a3a6efb492025-08-20T02:04:00ZengElsevierEcotoxicology and Environmental Safety0147-65132025-02-0129111786110.1016/j.ecoenv.2025.117861Causal effects of key air pollutants and meteorology on ischemic stroke onset: A convergent cross-mapping approachCheng Zhou0Haoran Li1Yang Hu2Bingyin Zhang3Pinxian Ren4Zhe Kan5Xianjie Jia6Jing Mi7Xiaolei Guo8Department of Epidemiology and Statistics, Bengbu Medical University, Bengbu, ChinaDepartment of Epidemiology and Statistics, Bengbu Medical University, Bengbu, ChinaDepartment of Epidemiology and Statistics, Bengbu Medical University, Bengbu, ChinaShandong Center for Disease Control and Prevention, Jinan, ChinaDepartment of Epidemiology and Statistics, Bengbu Medical University, Bengbu, ChinaDepartment of Epidemiology and Statistics, Bengbu Medical University, Bengbu, ChinaDepartment of Epidemiology and Statistics, Bengbu Medical University, Bengbu, ChinaDepartment of Epidemiology and Statistics, Bengbu Medical University, Bengbu, China; Correspondence to: Department of Epidemiology and Statistics, School of Public Health, Bengbu Medical University, No. 2600 Donghai Avenue, Long zi hu District, Bengbu 233000, China.Shandong Center for Disease Control and Prevention, Jinan, China; Correspondence to: Shandong Center for Disease Control and Prevention, No 16992 Jingshi Road, Lixia district, Jinan 250014, China.Background: Evidence suggests that environmental factors may influence the risk of ischemic stroke(IS).11 ischemic stroke(IS). Nevertheless, the majority of existing research has concentrated on correlation analysis, with only a limited number of studies employing specific methodologies to investigate the causal dynamics of this relationship with external drivers. Method: In this study, we employed an approach known as convergent cross-mapping to identify and elucidate the causal effects of significant air pollutants and meteorological factors on the pathogenesis of IS. The city of Shouguang in the Shandong Peninsula region was selected for this study, primarily because of the environmental characteristics of the region and the notable prevalence of cases during the study period. Results: Key air pollutants and several meteorological factors in the region have a causal effects on IS. A general trend can be drawn. SO222 sulfur dioxide(SO2) (ρ = 0.215, ∂=0.016), PM2.533 Particulate matter with a diameter< 2.5 μm(PM2.5) (ρ = 0.077, ∂=0.002), and PM1044 Particulate matter with a diameter< 10 μm(PM10) (ρ = 0.058, ∂=0.0014) had a positive causal effects on IS,and relative humidity (ρ = 0.050, ∂=-0.009) tended to reduce the number of IS cases. Conclusion: Through this case study, a causal network was developed with the aim of integrating the study of the interactions between variables and providing a clear model to aid the management of IS.http://www.sciencedirect.com/science/article/pii/S0147651325001976Empirical dynamic modelingAir pollutantsischemic strokeCausality |
| spellingShingle | Cheng Zhou Haoran Li Yang Hu Bingyin Zhang Pinxian Ren Zhe Kan Xianjie Jia Jing Mi Xiaolei Guo Causal effects of key air pollutants and meteorology on ischemic stroke onset: A convergent cross-mapping approach Ecotoxicology and Environmental Safety Empirical dynamic modeling Air pollutants ischemic stroke Causality |
| title | Causal effects of key air pollutants and meteorology on ischemic stroke onset: A convergent cross-mapping approach |
| title_full | Causal effects of key air pollutants and meteorology on ischemic stroke onset: A convergent cross-mapping approach |
| title_fullStr | Causal effects of key air pollutants and meteorology on ischemic stroke onset: A convergent cross-mapping approach |
| title_full_unstemmed | Causal effects of key air pollutants and meteorology on ischemic stroke onset: A convergent cross-mapping approach |
| title_short | Causal effects of key air pollutants and meteorology on ischemic stroke onset: A convergent cross-mapping approach |
| title_sort | causal effects of key air pollutants and meteorology on ischemic stroke onset a convergent cross mapping approach |
| topic | Empirical dynamic modeling Air pollutants ischemic stroke Causality |
| url | http://www.sciencedirect.com/science/article/pii/S0147651325001976 |
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