Yeast Nat4 regulates DNA damage checkpoint signaling through its N-terminal acetyltransferase activity on histone H4.

The DNA damage response (DDR) constitutes a vital cellular process that safeguards genome integrity. This biological process involves substantial alterations in chromatin structure, commonly orchestrated by epigenetic enzymes. Here, we show that the epigenetic modifier N-terminal acetyltransferase 4...

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Bibliographic Details
Main Authors: Mamantia Constantinou, Evelina Charidemou, Izge Shanlitourk, Katerina Strati, Antonis Kirmizis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-10-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011433
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