Exploring the potential clinical value of shear wave elastography in prostate cancer: a meta-analysis
Abstract The potential role of shear wave elastography (SWE) in prostate cancer (PCa) remains unclear. We systematically searched PubMed, Web of Science, and the Cochrane Library databases to identify correlated studies up to Dec 2024. A total of 137 studies were identified for potential inclusion,...
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| Format: | Article |
| Language: | English |
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BMC
2025-07-01
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| Series: | BMC Cancer |
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| Online Access: | https://doi.org/10.1186/s12885-025-14414-3 |
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| author | Danli Liu Weilong Lin Cailiu Wei Yiqi Huang Fenjuan Chen Yanling Zhang Feifei Pu |
| author_facet | Danli Liu Weilong Lin Cailiu Wei Yiqi Huang Fenjuan Chen Yanling Zhang Feifei Pu |
| author_sort | Danli Liu |
| collection | DOAJ |
| description | Abstract The potential role of shear wave elastography (SWE) in prostate cancer (PCa) remains unclear. We systematically searched PubMed, Web of Science, and the Cochrane Library databases to identify correlated studies up to Dec 2024. A total of 137 studies were identified for potential inclusion, and 11 studies were included, comprising 1551 PCa patients. The pooled sensitivity, specificity, and the area under the summary receiver operating characteristic curve (AUC) for detecting malignant prostatic nodules were 90% (95% CI, 81–95%), 75% (95% CI, 62–84%) and 90% (95% CI: 87, 92%) in per-patient analysis, respectively. The sensitivity, specificity, and AUC were 86% (95% CI: 72%, 95%), 86% (95% CI: 78%, 92%) and 92% (95% CI: 90%, 94%) in per-sextant analysis. Publication bias test addressed low significant small-study bias. We found that SWE may serve as a potential diagnostic strategy for PCa and may help to reduce the number of core biopsies. Since limited quantity and small sample size of included studies, further well-designed studies are strongly encouraged to address this promising strategy. |
| format | Article |
| id | doaj-art-7edc680ab1d54ebf82fefe38565ed6ea |
| institution | Kabale University |
| issn | 1471-2407 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj-art-7edc680ab1d54ebf82fefe38565ed6ea2025-08-20T04:01:36ZengBMCBMC Cancer1471-24072025-07-0125111210.1186/s12885-025-14414-3Exploring the potential clinical value of shear wave elastography in prostate cancer: a meta-analysisDanli Liu0Weilong Lin1Cailiu Wei2Yiqi Huang3Fenjuan Chen4Yanling Zhang5Feifei Pu6Department of Oncology, Shaoxing Second HospitalDepartment of Urology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen UniversityAffiliated Hospital of YouJiang Medical University for NationalitiesDepartment of Nephrology, Shaoxing Second HospitalDepartment of Internal Medicine, Shaoxing Second HospitalDepartment of Nephrology, Shaoxing Second HospitalDepartment of Ultrasonic, Shaoxing Second HospitalAbstract The potential role of shear wave elastography (SWE) in prostate cancer (PCa) remains unclear. We systematically searched PubMed, Web of Science, and the Cochrane Library databases to identify correlated studies up to Dec 2024. A total of 137 studies were identified for potential inclusion, and 11 studies were included, comprising 1551 PCa patients. The pooled sensitivity, specificity, and the area under the summary receiver operating characteristic curve (AUC) for detecting malignant prostatic nodules were 90% (95% CI, 81–95%), 75% (95% CI, 62–84%) and 90% (95% CI: 87, 92%) in per-patient analysis, respectively. The sensitivity, specificity, and AUC were 86% (95% CI: 72%, 95%), 86% (95% CI: 78%, 92%) and 92% (95% CI: 90%, 94%) in per-sextant analysis. Publication bias test addressed low significant small-study bias. We found that SWE may serve as a potential diagnostic strategy for PCa and may help to reduce the number of core biopsies. Since limited quantity and small sample size of included studies, further well-designed studies are strongly encouraged to address this promising strategy.https://doi.org/10.1186/s12885-025-14414-3Shear wave elastographyProstate cancerDiagnosticAUCMeta-analysis |
| spellingShingle | Danli Liu Weilong Lin Cailiu Wei Yiqi Huang Fenjuan Chen Yanling Zhang Feifei Pu Exploring the potential clinical value of shear wave elastography in prostate cancer: a meta-analysis BMC Cancer Shear wave elastography Prostate cancer Diagnostic AUC Meta-analysis |
| title | Exploring the potential clinical value of shear wave elastography in prostate cancer: a meta-analysis |
| title_full | Exploring the potential clinical value of shear wave elastography in prostate cancer: a meta-analysis |
| title_fullStr | Exploring the potential clinical value of shear wave elastography in prostate cancer: a meta-analysis |
| title_full_unstemmed | Exploring the potential clinical value of shear wave elastography in prostate cancer: a meta-analysis |
| title_short | Exploring the potential clinical value of shear wave elastography in prostate cancer: a meta-analysis |
| title_sort | exploring the potential clinical value of shear wave elastography in prostate cancer a meta analysis |
| topic | Shear wave elastography Prostate cancer Diagnostic AUC Meta-analysis |
| url | https://doi.org/10.1186/s12885-025-14414-3 |
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