Thymic B cells in aging and autoimmune disease

Thymic B cells in aging and autoimmune disease

Thymic B cells comprise a heterogenous population of cells localized primarily within the thymic medulla, a region populated by professional antigen-presenting cells (APCs) including dendritic cells, medullary thymic epithelial cells (mTECs), and macrophages. Through expression and presentation of s...

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Bibliographic Details
Main Authors: Sarah A. Wedemeyer, Ann V. Griffith
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
thymus
aging
B cells
autoimmune disease
tolerance
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1595805/full
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