The Effect of Arterial Elongation on Isolated Common Iliac Artery Pathologies

Purpose: to investigate the effects of vessel geometry on steno-occlusive and dilatative common iliac artery (CIA) pathologies. Methods: this single-center, retrospective study included 100 participants, namely 60 participants with a unilateral, isolated CIA pathology who were divided into three pat...

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Main Authors: Ádám Szőnyi, Balázs Bence Nyárády, Márton Philippovich, Adrienn Dobai, Ekrem Anil Sari, András Szőnyi, Anikó Ilona Nagy, Edit Dósa
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Life
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Online Access:https://www.mdpi.com/2075-1729/14/11/1440
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author Ádám Szőnyi
Balázs Bence Nyárády
Márton Philippovich
Adrienn Dobai
Ekrem Anil Sari
András Szőnyi
Anikó Ilona Nagy
Edit Dósa
author_facet Ádám Szőnyi
Balázs Bence Nyárády
Márton Philippovich
Adrienn Dobai
Ekrem Anil Sari
András Szőnyi
Anikó Ilona Nagy
Edit Dósa
author_sort Ádám Szőnyi
collection DOAJ
description Purpose: to investigate the effects of vessel geometry on steno-occlusive and dilatative common iliac artery (CIA) pathologies. Methods: this single-center, retrospective study included 100 participants, namely 60 participants with a unilateral, isolated CIA pathology who were divided into three pathology-based groups (a stenosis group, <i>n</i> = 20, an occlusion group, <i>n</i> = 20, and an aneurysm group, <i>n</i> = 20) and 40 participants without a CIA pathology (control group). All participants underwent abdominal and pelvic computed tomography angiography. The aortoiliac region of the participants was reconstructed into three-dimensional models. Elongation parameters (tortuosity index (TI) and absolute average curvature (AAC)) and bifurcation parameters (iliac take-off angle, iliac planarity angle, and bifurcation angle) were determined using an in-house-written piece of software. Demographic data, anthropometric data, cardiovascular risk factor data, and medical history data were obtained from participants’ electronic health records. The following statistical methods were used: one-way ANOVA, chi-square test, <i>t</i>-tests, Wilcoxon test, Kruskal–Wallis test, and multivariate linear regression. Results: in the occlusion group, both TI and AAC values were significantly higher on the contralateral side than on the ipsilateral side (both <i>p</i> < 0.001), whereas in the aneurysm group the AAC values were significantly higher on the ipsilateral side than on the contralateral side (<i>p</i> = 0.001). The ipsilateral and contralateral TI and AAC values of the iliac arteries were significantly higher in the aneurysm group than in the other three groups (all <i>p</i> < 0.001). Age significantly affected all of the elongation parameters except for the TI of the infrarenal aorta (all <i>p</i> < 0.010 except the TI of the infrarenal aorta). In addition, the AAC values for the iliac arteries were significantly associated with obesity (ipsilateral iliac artery, <i>p</i> = 0.045; contralateral iliac artery, <i>p</i> = 0.047). Aortic bifurcation parameters did not differ significantly either within each group (ipsilateral versus contralateral side) or between the individual groups. Conclusions: occlusions tend to develop in relatively straight iliac arteries, whereas unilateral, isolated CIA aneurysms are more likely to occur in elongated aortoiliac systems.
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spelling doaj-art-7ecdd9b2353346319a7db17855347f622025-08-20T02:47:59ZengMDPI AGLife2075-17292024-11-011411144010.3390/life14111440The Effect of Arterial Elongation on Isolated Common Iliac Artery PathologiesÁdám Szőnyi0Balázs Bence Nyárády1Márton Philippovich2Adrienn Dobai3Ekrem Anil Sari4András Szőnyi5Anikó Ilona Nagy6Edit Dósa7Heart and Vascular Center, Semmelweis University, 1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, 1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, 1122 Budapest, HungaryDepartment of Oral Diagnostics, Semmelweis University, 1088 Budapest, HungaryDokuz Eylül University Research and Application Hospital, 35330 Izmir, TurkeyGottsegen National Cardiovascular Center, 1096 Budapest, HungaryHeart and Vascular Center, Semmelweis University, 1122 Budapest, HungaryHeart and Vascular Center, Semmelweis University, 1122 Budapest, HungaryPurpose: to investigate the effects of vessel geometry on steno-occlusive and dilatative common iliac artery (CIA) pathologies. Methods: this single-center, retrospective study included 100 participants, namely 60 participants with a unilateral, isolated CIA pathology who were divided into three pathology-based groups (a stenosis group, <i>n</i> = 20, an occlusion group, <i>n</i> = 20, and an aneurysm group, <i>n</i> = 20) and 40 participants without a CIA pathology (control group). All participants underwent abdominal and pelvic computed tomography angiography. The aortoiliac region of the participants was reconstructed into three-dimensional models. Elongation parameters (tortuosity index (TI) and absolute average curvature (AAC)) and bifurcation parameters (iliac take-off angle, iliac planarity angle, and bifurcation angle) were determined using an in-house-written piece of software. Demographic data, anthropometric data, cardiovascular risk factor data, and medical history data were obtained from participants’ electronic health records. The following statistical methods were used: one-way ANOVA, chi-square test, <i>t</i>-tests, Wilcoxon test, Kruskal–Wallis test, and multivariate linear regression. Results: in the occlusion group, both TI and AAC values were significantly higher on the contralateral side than on the ipsilateral side (both <i>p</i> < 0.001), whereas in the aneurysm group the AAC values were significantly higher on the ipsilateral side than on the contralateral side (<i>p</i> = 0.001). The ipsilateral and contralateral TI and AAC values of the iliac arteries were significantly higher in the aneurysm group than in the other three groups (all <i>p</i> < 0.001). Age significantly affected all of the elongation parameters except for the TI of the infrarenal aorta (all <i>p</i> < 0.010 except the TI of the infrarenal aorta). In addition, the AAC values for the iliac arteries were significantly associated with obesity (ipsilateral iliac artery, <i>p</i> = 0.045; contralateral iliac artery, <i>p</i> = 0.047). Aortic bifurcation parameters did not differ significantly either within each group (ipsilateral versus contralateral side) or between the individual groups. Conclusions: occlusions tend to develop in relatively straight iliac arteries, whereas unilateral, isolated CIA aneurysms are more likely to occur in elongated aortoiliac systems.https://www.mdpi.com/2075-1729/14/11/1440aortailiac arterieselongationtortuositycurvaturestenosis
spellingShingle Ádám Szőnyi
Balázs Bence Nyárády
Márton Philippovich
Adrienn Dobai
Ekrem Anil Sari
András Szőnyi
Anikó Ilona Nagy
Edit Dósa
The Effect of Arterial Elongation on Isolated Common Iliac Artery Pathologies
Life
aorta
iliac arteries
elongation
tortuosity
curvature
stenosis
title The Effect of Arterial Elongation on Isolated Common Iliac Artery Pathologies
title_full The Effect of Arterial Elongation on Isolated Common Iliac Artery Pathologies
title_fullStr The Effect of Arterial Elongation on Isolated Common Iliac Artery Pathologies
title_full_unstemmed The Effect of Arterial Elongation on Isolated Common Iliac Artery Pathologies
title_short The Effect of Arterial Elongation on Isolated Common Iliac Artery Pathologies
title_sort effect of arterial elongation on isolated common iliac artery pathologies
topic aorta
iliac arteries
elongation
tortuosity
curvature
stenosis
url https://www.mdpi.com/2075-1729/14/11/1440
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