Stem cell therapy: a revolutionary cure or a pandora's box

Abstract This review article examines how stem cell therapies can cure various diseases and injuries while also discussing the difficulties and moral conundrums that come with their application. The article focuses on the revolutionary developments in stem cell research, especially the introduction...

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Main Author: Hany E. Marei
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-025-04334-1
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author Hany E. Marei
author_facet Hany E. Marei
author_sort Hany E. Marei
collection DOAJ
description Abstract This review article examines how stem cell therapies can cure various diseases and injuries while also discussing the difficulties and moral conundrums that come with their application. The article focuses on the revolutionary developments in stem cell research, especially the introduction of gene editing tools like CRISPR-Cas9, which can potentially improve the safety and effectiveness of stem cell-based treatments. To guarantee the responsible use of stem cells in clinical applications, it is also argued that standardizing clinical procedures and fortifying ethical and regulatory frameworks are essential first steps. The assessment also highlights the substantial obstacles that still need to be addressed, such as the moral dilemmas raised by the use of embryonic stem cells, the dangers of unlicensed stem cell clinics, and the difficulties in obtaining and paying for care for patients. The study emphasizes how critical it is to address these problems to stop exploitation, guarantee patient safety, and increase the accessibility of stem cell therapy. The review also addresses the significance of thorough clinical trials, public education, and policy development to guarantee that stem cell research may fulfill its full potential. The review concludes by describing stem cell research as a promising but complicated topic that necessitates a thorough evaluation of both the hazards and the benefits. To overcome the ethical, legal, and accessibility obstacles and eventually guarantee that stem cell treatments may be safely and fairly included in conventional healthcare, it urges cooperation between the scientific community, legislators, and the general public.
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spelling doaj-art-7ecd92cc320b49d69caa21c0220c8e522025-08-20T03:08:40ZengBMCStem Cell Research & Therapy1757-65122025-05-0116112410.1186/s13287-025-04334-1Stem cell therapy: a revolutionary cure or a pandora's boxHany E. Marei0Department of Cytology and Histology, Faculty of Veterinary Medicine, Mansoura UniversityAbstract This review article examines how stem cell therapies can cure various diseases and injuries while also discussing the difficulties and moral conundrums that come with their application. The article focuses on the revolutionary developments in stem cell research, especially the introduction of gene editing tools like CRISPR-Cas9, which can potentially improve the safety and effectiveness of stem cell-based treatments. To guarantee the responsible use of stem cells in clinical applications, it is also argued that standardizing clinical procedures and fortifying ethical and regulatory frameworks are essential first steps. The assessment also highlights the substantial obstacles that still need to be addressed, such as the moral dilemmas raised by the use of embryonic stem cells, the dangers of unlicensed stem cell clinics, and the difficulties in obtaining and paying for care for patients. The study emphasizes how critical it is to address these problems to stop exploitation, guarantee patient safety, and increase the accessibility of stem cell therapy. The review also addresses the significance of thorough clinical trials, public education, and policy development to guarantee that stem cell research may fulfill its full potential. The review concludes by describing stem cell research as a promising but complicated topic that necessitates a thorough evaluation of both the hazards and the benefits. To overcome the ethical, legal, and accessibility obstacles and eventually guarantee that stem cell treatments may be safely and fairly included in conventional healthcare, it urges cooperation between the scientific community, legislators, and the general public.https://doi.org/10.1186/s13287-025-04334-1Stem cell researchRegenerative medicineInduced pluripotent stem cells (iPSCs)Embryonic stem cells (ESCs)Mesenchymal stem cells (MSCs)Hematopoietic stem cells (HSCs)
spellingShingle Hany E. Marei
Stem cell therapy: a revolutionary cure or a pandora's box
Stem Cell Research & Therapy
Stem cell research
Regenerative medicine
Induced pluripotent stem cells (iPSCs)
Embryonic stem cells (ESCs)
Mesenchymal stem cells (MSCs)
Hematopoietic stem cells (HSCs)
title Stem cell therapy: a revolutionary cure or a pandora's box
title_full Stem cell therapy: a revolutionary cure or a pandora's box
title_fullStr Stem cell therapy: a revolutionary cure or a pandora's box
title_full_unstemmed Stem cell therapy: a revolutionary cure or a pandora's box
title_short Stem cell therapy: a revolutionary cure or a pandora's box
title_sort stem cell therapy a revolutionary cure or a pandora s box
topic Stem cell research
Regenerative medicine
Induced pluripotent stem cells (iPSCs)
Embryonic stem cells (ESCs)
Mesenchymal stem cells (MSCs)
Hematopoietic stem cells (HSCs)
url https://doi.org/10.1186/s13287-025-04334-1
work_keys_str_mv AT hanyemarei stemcelltherapyarevolutionarycureorapandorasbox