Current research status of Raman spectroscopy in glioma detection

Glioma is the most common primary tumor of the nervous system. Conventional diagnostic methods for glioma often involve time-consuming or reliance on externally introduced materials. Consequently, there is an urgent need for rapid and reliable diagnostic techniques. Raman spectroscopy has emerged as...

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Main Authors: Jie Liu, Pan Wang, Hua Zhang, Yuansen Guo, Mingjie Tang, Junwei Wang, Nan Wu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Photodiagnosis and Photodynamic Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1572100024004253
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author Jie Liu
Pan Wang
Hua Zhang
Yuansen Guo
Mingjie Tang
Junwei Wang
Nan Wu
author_facet Jie Liu
Pan Wang
Hua Zhang
Yuansen Guo
Mingjie Tang
Junwei Wang
Nan Wu
author_sort Jie Liu
collection DOAJ
description Glioma is the most common primary tumor of the nervous system. Conventional diagnostic methods for glioma often involve time-consuming or reliance on externally introduced materials. Consequently, there is an urgent need for rapid and reliable diagnostic techniques. Raman spectroscopy has emerged as a promising tool, offering rapid, accurate, and label-free analysis with high sensitivity and specificity in biomedical applications. In this review, the fundamental principles of Raman spectroscopy have been introduced, and then the progress of applying Raman spectroscopy in biomedical studies has been summarized, including the identification and typing of glioma. The challenges encountered in the clinical application of Raman spectroscopy for glioma have been discussed, and the prospects have also been envisioned.
format Article
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publishDate 2024-12-01
publisher Elsevier
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series Photodiagnosis and Photodynamic Therapy
spelling doaj-art-7ec768e9dca643a38f419dd1d0f60a812025-08-20T01:59:30ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002024-12-015010438810.1016/j.pdpdt.2024.104388Current research status of Raman spectroscopy in glioma detectionJie Liu0Pan Wang1Hua Zhang2Yuansen Guo3Mingjie Tang4Junwei Wang5Nan Wu6Department of Neurosurgery, Chongqing General Hospital, Chongqing University, Chongqing 401147, China; Chongqing Research Center for Glioma Precision Medicine, Chongqing University, Chongqing 401147, ChinaDepartment of Neurosurgery, Chongqing General Hospital, Chongqing University, Chongqing 401147, China; Chongqing Research Center for Glioma Precision Medicine, Chongqing University, Chongqing 401147, ChinaChongqing Institute of Green and Intelligent Technology, Chongqing University, Chongqing 400714, ChinaChongqing Institute of Green and Intelligent Technology, Chongqing University, Chongqing 400714, ChinaChongqing Institute of Green and Intelligent Technology, Chongqing University, Chongqing 400714, ChinaDepartment of Neurosurgery, Chongqing General Hospital, Chongqing University, Chongqing 401147, China; Chongqing Research Center for Glioma Precision Medicine, Chongqing University, Chongqing 401147, ChinaDepartment of Neurosurgery, Chongqing General Hospital, Chongqing University, Chongqing 401147, China; Chongqing Research Center for Glioma Precision Medicine, Chongqing University, Chongqing 401147, China; Corresponding author at: NO.118, Xingguang Avenue, Liangjiang New Aera, Chongqing 401147, China.Glioma is the most common primary tumor of the nervous system. Conventional diagnostic methods for glioma often involve time-consuming or reliance on externally introduced materials. Consequently, there is an urgent need for rapid and reliable diagnostic techniques. Raman spectroscopy has emerged as a promising tool, offering rapid, accurate, and label-free analysis with high sensitivity and specificity in biomedical applications. In this review, the fundamental principles of Raman spectroscopy have been introduced, and then the progress of applying Raman spectroscopy in biomedical studies has been summarized, including the identification and typing of glioma. The challenges encountered in the clinical application of Raman spectroscopy for glioma have been discussed, and the prospects have also been envisioned.http://www.sciencedirect.com/science/article/pii/S1572100024004253Raman spectroscopyGlioma detectionHistological typingMolecular typing
spellingShingle Jie Liu
Pan Wang
Hua Zhang
Yuansen Guo
Mingjie Tang
Junwei Wang
Nan Wu
Current research status of Raman spectroscopy in glioma detection
Photodiagnosis and Photodynamic Therapy
Raman spectroscopy
Glioma detection
Histological typing
Molecular typing
title Current research status of Raman spectroscopy in glioma detection
title_full Current research status of Raman spectroscopy in glioma detection
title_fullStr Current research status of Raman spectroscopy in glioma detection
title_full_unstemmed Current research status of Raman spectroscopy in glioma detection
title_short Current research status of Raman spectroscopy in glioma detection
title_sort current research status of raman spectroscopy in glioma detection
topic Raman spectroscopy
Glioma detection
Histological typing
Molecular typing
url http://www.sciencedirect.com/science/article/pii/S1572100024004253
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