Diffuse-type Gastric Cancer

Gastric cancer is the most prevalent malignant tumor in Korea. Histologically, it is often classified into intestinal-type and diffuse-type. Intestinal-type gastric cancer is known to occur mainly from chronic gastritis caused by Helicobacter pylori (H. pylori) through atrophic gastritis and intesti...

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Main Author: Jie-Hyun Kim
Format: Article
Language:English
Published: Korean College of Helicobacter and Upper Gastrointestinal Research 2022-03-01
Series:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
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Online Access:http://helicojournal.org/upload/pdf/kjhugr-2022-0072.pdf
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author Jie-Hyun Kim
author_facet Jie-Hyun Kim
author_sort Jie-Hyun Kim
collection DOAJ
description Gastric cancer is the most prevalent malignant tumor in Korea. Histologically, it is often classified into intestinal-type and diffuse-type. Intestinal-type gastric cancer is known to occur mainly from chronic gastritis caused by Helicobacter pylori (H. pylori) through atrophic gastritis and intestinal metaplasia, a precancerous change of the mucosa, whereas diffuse-type gastric cancer is caused by H. pylori infection, wherein active inflammation of the gastric mucosa occurs without precancerous changes in the mucosa. Compared with intestinal-type gastric cancer, it occurs at a young age, there is no difference in male to female ratio, or tends to occur more in women, and is more aggressive than intestinal-type gastric cancer. Intestinal-type gastric cancer is predominant in East Asian populations such as Koreans and Japanese, whereas diffuse-type gastric cancer has more uniform geographic distribution. In the present manuscript, I have reviewed diffuse-type gastric cancer, distinct from intestinal-type gastric cancer.
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publisher Korean College of Helicobacter and Upper Gastrointestinal Research
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series The Korean Journal of Helicobacter and Upper Gastrointestinal Research
spelling doaj-art-7ea23b8f0d624ddf87708babdc79adfe2025-08-20T03:33:39ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312022-03-01221111710.7704/kjhugr.2022.0072718Diffuse-type Gastric CancerJie-Hyun KimGastric cancer is the most prevalent malignant tumor in Korea. Histologically, it is often classified into intestinal-type and diffuse-type. Intestinal-type gastric cancer is known to occur mainly from chronic gastritis caused by Helicobacter pylori (H. pylori) through atrophic gastritis and intestinal metaplasia, a precancerous change of the mucosa, whereas diffuse-type gastric cancer is caused by H. pylori infection, wherein active inflammation of the gastric mucosa occurs without precancerous changes in the mucosa. Compared with intestinal-type gastric cancer, it occurs at a young age, there is no difference in male to female ratio, or tends to occur more in women, and is more aggressive than intestinal-type gastric cancer. Intestinal-type gastric cancer is predominant in East Asian populations such as Koreans and Japanese, whereas diffuse-type gastric cancer has more uniform geographic distribution. In the present manuscript, I have reviewed diffuse-type gastric cancer, distinct from intestinal-type gastric cancer.http://helicojournal.org/upload/pdf/kjhugr-2022-0072.pdfcarcinogenesisclassificationhelicobacter pyloripathologystomach neoplasms
spellingShingle Jie-Hyun Kim
Diffuse-type Gastric Cancer
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
carcinogenesis
classification
helicobacter pylori
pathology
stomach neoplasms
title Diffuse-type Gastric Cancer
title_full Diffuse-type Gastric Cancer
title_fullStr Diffuse-type Gastric Cancer
title_full_unstemmed Diffuse-type Gastric Cancer
title_short Diffuse-type Gastric Cancer
title_sort diffuse type gastric cancer
topic carcinogenesis
classification
helicobacter pylori
pathology
stomach neoplasms
url http://helicojournal.org/upload/pdf/kjhugr-2022-0072.pdf
work_keys_str_mv AT jiehyunkim diffusetypegastriccancer