Determination of rutin, hyperoside, quercetin in Xiang lotus by HPLC

<b>Objective:</b> To establish a HPLC method for simultaneous determination of rutin, hyperoside, quercetin in Xiang lotus. <b>Methods:</b> The HPLC method was performed on an Agilent ZORBAX SB-C<sub>18</sub> column (4.6 mm×250 mm, 5 m) with gradient elution of me...

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Main Authors: ZHONG Feifei, LI Jing, LEI Deqing, YANG Yun, WU Jianfang, OUYANG Li
Format: Article
Language:English
Published: The Editorial Office of Food and Machinery 2023-10-01
Series:Shipin yu jixie
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Online Access:http://www.ifoodmm.com/spyjxen/article/abstract/20230910
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author ZHONG Feifei
LI Jing
LEI Deqing
YANG Yun
WU Jianfang
OUYANG Li
author_facet ZHONG Feifei
LI Jing
LEI Deqing
YANG Yun
WU Jianfang
OUYANG Li
author_sort ZHONG Feifei
collection DOAJ
description <b>Objective:</b> To establish a HPLC method for simultaneous determination of rutin, hyperoside, quercetin in Xiang lotus. <b>Methods:</b> The HPLC method was performed on an Agilent ZORBAX SB-C<sub>18</sub> column (4.6 mm×250 mm, 5 m) with gradient elution of methanol and 0.6% phosphoric acid solution. The flow rate was 1.0 mL/min. The column temperature was 30 ℃ and the detection wavelength was set at 255 nm. <b>Results:</b> The contents of rutin, hypericin and quercetin in 20 batches of lotus samples were 1.32~2.06, 1.36~2.43, 1.41~3.26 mg/kg, respectively. The linear range of the concentration of rutin, hypericin and quercetin was 5~200 g/mL (<i>R</i><sup>2</sup>=0.999 9), the three flavonoids showed a good linearity, a high sensitivity, and good serviceability. The relative standard deviation (RSD) for precision, stability, repeatability, and recoveries test were all less than 4.0%, and the average recovery rate of added standard were 96.6%, 96.9%, 97.4%, respecitvely. <b>Conclusion:</b> The method is convenient and accurate, and can be used for the content determination and quality evaluation of flavonoids in Xiang lotus.
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publisher The Editorial Office of Food and Machinery
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spelling doaj-art-7e8a346cfdde4b9d81011cf7c3477a192025-08-20T02:23:31ZengThe Editorial Office of Food and MachineryShipin yu jixie1003-57882023-10-01399576410.13652/j.spjx.1003.5788.2023.80595Determination of rutin, hyperoside, quercetin in Xiang lotus by HPLCZHONG Feifei0LI Jing1LEI Deqing2YANG Yun3WU Jianfang4OUYANG Li5 Changsha Institute for Food and Drug Control, Changsha, Hunan 410008 , China Changsha Institute for Food and Drug Control, Changsha, Hunan 410008 , China Changsha Institute for Food and Drug Control, Changsha, Hunan 410008 , China Changsha Institute for Food and Drug Control, Changsha, Hunan 410008 , China Changsha Institute for Food and Drug Control, Changsha, Hunan 410008 , China Changsha Institute for Food and Drug Control, Changsha, Hunan 410008 , China <b>Objective:</b> To establish a HPLC method for simultaneous determination of rutin, hyperoside, quercetin in Xiang lotus. <b>Methods:</b> The HPLC method was performed on an Agilent ZORBAX SB-C<sub>18</sub> column (4.6 mm×250 mm, 5 m) with gradient elution of methanol and 0.6% phosphoric acid solution. The flow rate was 1.0 mL/min. The column temperature was 30 ℃ and the detection wavelength was set at 255 nm. <b>Results:</b> The contents of rutin, hypericin and quercetin in 20 batches of lotus samples were 1.32~2.06, 1.36~2.43, 1.41~3.26 mg/kg, respectively. The linear range of the concentration of rutin, hypericin and quercetin was 5~200 g/mL (<i>R</i><sup>2</sup>=0.999 9), the three flavonoids showed a good linearity, a high sensitivity, and good serviceability. The relative standard deviation (RSD) for precision, stability, repeatability, and recoveries test were all less than 4.0%, and the average recovery rate of added standard were 96.6%, 96.9%, 97.4%, respecitvely. <b>Conclusion:</b> The method is convenient and accurate, and can be used for the content determination and quality evaluation of flavonoids in Xiang lotus.http://www.ifoodmm.com/spyjxen/article/abstract/20230910 xiang lotus hplc rutin hyperoside quercetin
spellingShingle ZHONG Feifei
LI Jing
LEI Deqing
YANG Yun
WU Jianfang
OUYANG Li
Determination of rutin, hyperoside, quercetin in Xiang lotus by HPLC
Shipin yu jixie
xiang lotus
hplc
rutin
hyperoside
quercetin
title Determination of rutin, hyperoside, quercetin in Xiang lotus by HPLC
title_full Determination of rutin, hyperoside, quercetin in Xiang lotus by HPLC
title_fullStr Determination of rutin, hyperoside, quercetin in Xiang lotus by HPLC
title_full_unstemmed Determination of rutin, hyperoside, quercetin in Xiang lotus by HPLC
title_short Determination of rutin, hyperoside, quercetin in Xiang lotus by HPLC
title_sort determination of rutin hyperoside quercetin in xiang lotus by hplc
topic xiang lotus
hplc
rutin
hyperoside
quercetin
url http://www.ifoodmm.com/spyjxen/article/abstract/20230910
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AT lijing determinationofrutinhyperosidequercetininxianglotusbyhplc
AT leideqing determinationofrutinhyperosidequercetininxianglotusbyhplc
AT yangyun determinationofrutinhyperosidequercetininxianglotusbyhplc
AT wujianfang determinationofrutinhyperosidequercetininxianglotusbyhplc
AT ouyangli determinationofrutinhyperosidequercetininxianglotusbyhplc