Vascular changes in the retina in patients with chronic respiratory insufficiency
Background/Aim. Chronic respiratory insufficiency is a pathological state which occurs as a result of respiratory system inability to maintain normal gas exchange between the outside air and circulating blood. For the purposes of human organism’s proper functioning, it is necessary that a c...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2014-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501412132A.pdf |
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| author | Adžić-Zečević Antoaneta Milojko Biljana Janićijević-Petrović Mirjana A. |
| author_facet | Adžić-Zečević Antoaneta Milojko Biljana Janićijević-Petrović Mirjana A. |
| author_sort | Adžić-Zečević Antoaneta |
| collection | DOAJ |
| description | Background/Aim. Chronic respiratory insufficiency is a pathological state
which occurs as a result of respiratory system inability to maintain normal
gas exchange between the outside air and circulating blood. For the purposes
of human organism’s proper functioning, it is necessary that a certain amount
of air in the lungs comes into contact with a certain amount of blood within
a unit of time, so that an adequate hemoglobin oxygenation could be achieved.
Then, hemoglobin from erythrocytes in the blood supply delivers oxygen to all
the tissues and cells of the body including the eye. Direct impact of
hypoxemia and hypercapnia on the wall of arterioles, venules and capillaries
results in a severe vasodilatation along with the increased permeability of
the walls causing clinically evident changes in the retina. The aim of this
study was to determine the degree of ocular changes in retina with patients
suffering from chronic respiratory insufficiency. Methods. A prospective
study was conducted on 80 patients, 40 patients with respiratory failure and
40 patients with chronic obstructive pulmonary disease an and bronchial
asthma (the control group). In all the patients direct and indirect
ophthalmoscopy and fluoresceine angiography was performed. Clinically visible
fundus and retina changes in patients suffering from chronic respiratory
failure were categorized as mild (dilatation and retinal veins and arteries
tortosion up to the mid-periphery), moderate (retinal hemorrhage) and severe
(optic nerve edema, macular edema, superficial and deep retinal hemorrhages
and venous occlusion). Results. In the patients suffering from respiratory
insufficiency the changes in retinal blood vessels were found [in 18 (45%)
mild, in 13 (32.5%) moderate, and in 9 (22%) severe], while in the patients
with chronic obstructive pulmonary disease and bronchial asthma (without
respiratory insufficiency) no changes were recognized. Conclusion. The
results of this study indicate the need for ophthalmologic examination in
patients with chronic respiratory insufficiency. It is important to
recognize, identify and quantify the changes on retinal blood vessels which
are clinically significant. It is necessary to provide their monitoring and
to prescribe proper therapeutic treatment in order to preserve visual
functions. |
| format | Article |
| id | doaj-art-7e855689308146b2aad4034949c4a12a |
| institution | DOAJ |
| issn | 0042-8450 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-7e855689308146b2aad4034949c4a12a2025-08-20T03:06:55ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502014-01-0171121132113710.2298/VSP1412132A0042-84501412132AVascular changes in the retina in patients with chronic respiratory insufficiencyAdžić-Zečević Antoaneta0Milojko Biljana1Janićijević-Petrović Mirjana A.2Clinical Center of Montenegro, Eye Clinic, Podgorica, MontenegroSpecial Hospital for Lung Diesease “Dr Jovan Bulajić”, Brezovik, MontenegroClinical Center Kragujevac, Clinic of Ophthalmology, KragujevacBackground/Aim. Chronic respiratory insufficiency is a pathological state which occurs as a result of respiratory system inability to maintain normal gas exchange between the outside air and circulating blood. For the purposes of human organism’s proper functioning, it is necessary that a certain amount of air in the lungs comes into contact with a certain amount of blood within a unit of time, so that an adequate hemoglobin oxygenation could be achieved. Then, hemoglobin from erythrocytes in the blood supply delivers oxygen to all the tissues and cells of the body including the eye. Direct impact of hypoxemia and hypercapnia on the wall of arterioles, venules and capillaries results in a severe vasodilatation along with the increased permeability of the walls causing clinically evident changes in the retina. The aim of this study was to determine the degree of ocular changes in retina with patients suffering from chronic respiratory insufficiency. Methods. A prospective study was conducted on 80 patients, 40 patients with respiratory failure and 40 patients with chronic obstructive pulmonary disease an and bronchial asthma (the control group). In all the patients direct and indirect ophthalmoscopy and fluoresceine angiography was performed. Clinically visible fundus and retina changes in patients suffering from chronic respiratory failure were categorized as mild (dilatation and retinal veins and arteries tortosion up to the mid-periphery), moderate (retinal hemorrhage) and severe (optic nerve edema, macular edema, superficial and deep retinal hemorrhages and venous occlusion). Results. In the patients suffering from respiratory insufficiency the changes in retinal blood vessels were found [in 18 (45%) mild, in 13 (32.5%) moderate, and in 9 (22%) severe], while in the patients with chronic obstructive pulmonary disease and bronchial asthma (without respiratory insufficiency) no changes were recognized. Conclusion. The results of this study indicate the need for ophthalmologic examination in patients with chronic respiratory insufficiency. It is important to recognize, identify and quantify the changes on retinal blood vessels which are clinically significant. It is necessary to provide their monitoring and to prescribe proper therapeutic treatment in order to preserve visual functions.http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501412132A.pdfrespiratory insufficiencypulmonary disease, chronic obstructiveanoxiaretinal diseaseoptic nerve |
| spellingShingle | Adžić-Zečević Antoaneta Milojko Biljana Janićijević-Petrović Mirjana A. Vascular changes in the retina in patients with chronic respiratory insufficiency Vojnosanitetski Pregled respiratory insufficiency pulmonary disease, chronic obstructive anoxia retinal disease optic nerve |
| title | Vascular changes in the retina in patients with chronic respiratory insufficiency |
| title_full | Vascular changes in the retina in patients with chronic respiratory insufficiency |
| title_fullStr | Vascular changes in the retina in patients with chronic respiratory insufficiency |
| title_full_unstemmed | Vascular changes in the retina in patients with chronic respiratory insufficiency |
| title_short | Vascular changes in the retina in patients with chronic respiratory insufficiency |
| title_sort | vascular changes in the retina in patients with chronic respiratory insufficiency |
| topic | respiratory insufficiency pulmonary disease, chronic obstructive anoxia retinal disease optic nerve |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501412132A.pdf |
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