A Silent Infection Pandemic of COVID-19: Epidemiological Investigation and Hypothetical Models

To explore the epidemic mode of COVID-19, we made an epidemiological investigation, set up hypothetical models, and compared them with hepatitis A virus (HAV) age-specific epidemic characteristic. In the epidemiological investigation, we reported the first familial COVID-19 silent infection in the w...

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Main Authors: Jianping Geng, Jun Yu, Tao Lu, Yinhe Wang, Yang Cao
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2020/5120253
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author Jianping Geng
Jun Yu
Tao Lu
Yinhe Wang
Yang Cao
author_facet Jianping Geng
Jun Yu
Tao Lu
Yinhe Wang
Yang Cao
author_sort Jianping Geng
collection DOAJ
description To explore the epidemic mode of COVID-19, we made an epidemiological investigation, set up hypothetical models, and compared them with hepatitis A virus (HAV) age-specific epidemic characteristic. In the epidemiological investigation, we reported the first familial COVID-19 silent infection in the world. A 19-year-old healthy female COVID-19 virus carrier without any symptoms caused two mild and one severe pneumonia. In hypothetical models, the silent infection rate ranges from 60% to 80% based on 3 sources: China mainland, evacuation of 4 nationals, and the ship “Diamond Princess,” respectively. In comparison with HAV, COVID-19 shows the same infection mode in children (aged 0–9 years), but significant difference in young adults (aged 10–44 years) and the elderly (aged 45 years or older). Therefore, we prejudged that COVID-19 is a silent infection pandemic mainly in young adults but threatens the elderly.
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institution Kabale University
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publishDate 2020-01-01
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series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-7e7fb3519b174e7ca17db4992912aacb2025-02-03T06:05:12ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95321918-14932020-01-01202010.1155/2020/51202535120253A Silent Infection Pandemic of COVID-19: Epidemiological Investigation and Hypothetical ModelsJianping Geng0Jun Yu1Tao Lu2Yinhe Wang3Yang Cao4Xi’an International Medical Center Hospital, Xi’an 710100, Shannxi, ChinaXi’an International Medical Center Hospital, Xi’an 710100, Shannxi, ChinaXi’an International Medical Center Hospital, Xi’an 710100, Shannxi, ChinaNanjing Drum Tower Hospital Affiliated to Nanjing University School of Medicine, Nanjing 210008, ChinaClinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro 70182, SwedenTo explore the epidemic mode of COVID-19, we made an epidemiological investigation, set up hypothetical models, and compared them with hepatitis A virus (HAV) age-specific epidemic characteristic. In the epidemiological investigation, we reported the first familial COVID-19 silent infection in the world. A 19-year-old healthy female COVID-19 virus carrier without any symptoms caused two mild and one severe pneumonia. In hypothetical models, the silent infection rate ranges from 60% to 80% based on 3 sources: China mainland, evacuation of 4 nationals, and the ship “Diamond Princess,” respectively. In comparison with HAV, COVID-19 shows the same infection mode in children (aged 0–9 years), but significant difference in young adults (aged 10–44 years) and the elderly (aged 45 years or older). Therefore, we prejudged that COVID-19 is a silent infection pandemic mainly in young adults but threatens the elderly.http://dx.doi.org/10.1155/2020/5120253
spellingShingle Jianping Geng
Jun Yu
Tao Lu
Yinhe Wang
Yang Cao
A Silent Infection Pandemic of COVID-19: Epidemiological Investigation and Hypothetical Models
Canadian Journal of Infectious Diseases and Medical Microbiology
title A Silent Infection Pandemic of COVID-19: Epidemiological Investigation and Hypothetical Models
title_full A Silent Infection Pandemic of COVID-19: Epidemiological Investigation and Hypothetical Models
title_fullStr A Silent Infection Pandemic of COVID-19: Epidemiological Investigation and Hypothetical Models
title_full_unstemmed A Silent Infection Pandemic of COVID-19: Epidemiological Investigation and Hypothetical Models
title_short A Silent Infection Pandemic of COVID-19: Epidemiological Investigation and Hypothetical Models
title_sort silent infection pandemic of covid 19 epidemiological investigation and hypothetical models
url http://dx.doi.org/10.1155/2020/5120253
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