Effect of Vitamin D on Fasting Blood Sugar and HbA1c in Type 2 Diabetes Mellitus Patients
ABSTRACT: Objective: To evaluate the impact of vitamin D supplementation on fasting blood sugar & HbA1c in Type-2 diabetes mellitus patients. Methodology: This was an analytical case control study and was carried out by the Pharmacology Department at the Basic Medical Sciences Institute (BMSI,...
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Aziz Fatimah Medical and Dental College
2024-12-01
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| Series: | Journal of Aziz Fatimah Medical and Dental College |
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| Online Access: | https://journal.afmdc.edu.pk/index.php/AFMDC/article/view/295 |
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| author | Rabab Zehra Zareen Naz Samina Mohyuddin Saima Zainab Aarfa Amjad Ittafaq Hussain |
| author_facet | Rabab Zehra Zareen Naz Samina Mohyuddin Saima Zainab Aarfa Amjad Ittafaq Hussain |
| author_sort | Rabab Zehra |
| collection | DOAJ |
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ABSTRACT:
Objective: To evaluate the impact of vitamin D supplementation on fasting blood sugar & HbA1c in Type-2 diabetes mellitus patients.
Methodology: This was an analytical case control study and was carried out by the Pharmacology Department at the Basic Medical Sciences Institute (BMSI, JPMC) with the collaboration of Diabetic OPD, JPMC, Karachi for the duration of 6 months. In this study 80 patients were selected by non-probability purposive sampling method and open EPI 3.01 version was used to estimate the sample size.
Results: The study revealed that pre and post plasma vitamin D proportions in the intervention group were significant (P<0.001) as compared to the group labeled as control which did not show any difference at the end of study (P=0.16). However, there was an insignificant relationship between Vit D and HbA1c with no improvement observed in glycemic control (P=0.74) or HbA1c levels (P=0.20) in the intervention group.
Conclusion: According to the study's findings, vitamin D addition has improved plasma vitamin D3 levels and improved insulin sensitivity in patients with T2DM. The current analysis did not find a significant contribution to reducing HbA1c or enhancing glycemic control in individuals with T2DM.
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| format | Article |
| id | doaj-art-7e7fa33efa424b9288acb99793099d67 |
| institution | Kabale University |
| issn | 2706-7238 2706-7246 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Aziz Fatimah Medical and Dental College |
| record_format | Article |
| series | Journal of Aziz Fatimah Medical and Dental College |
| spelling | doaj-art-7e7fa33efa424b9288acb99793099d672025-01-26T08:45:59ZengAziz Fatimah Medical and Dental CollegeJournal of Aziz Fatimah Medical and Dental College2706-72382706-72462024-12-016210.55279/jafmdc.v6i2.295Effect of Vitamin D on Fasting Blood Sugar and HbA1c in Type 2 Diabetes Mellitus PatientsRabab Zehra0 Zareen Naz1 Samina Mohyuddin2Saima Zainab 3Aarfa Amjad 4Ittafaq Hussain5Liaquat College of Medicine and DentistryLiaquat college of Medicine and DentistryLiaquat college of Medicine and DentistryLiaquat National Medical collegeBiological and Biomedical sciences department Agha Khan UniversityLiaquat college of Medicine and Dentistry ABSTRACT: Objective: To evaluate the impact of vitamin D supplementation on fasting blood sugar & HbA1c in Type-2 diabetes mellitus patients. Methodology: This was an analytical case control study and was carried out by the Pharmacology Department at the Basic Medical Sciences Institute (BMSI, JPMC) with the collaboration of Diabetic OPD, JPMC, Karachi for the duration of 6 months. In this study 80 patients were selected by non-probability purposive sampling method and open EPI 3.01 version was used to estimate the sample size. Results: The study revealed that pre and post plasma vitamin D proportions in the intervention group were significant (P<0.001) as compared to the group labeled as control which did not show any difference at the end of study (P=0.16). However, there was an insignificant relationship between Vit D and HbA1c with no improvement observed in glycemic control (P=0.74) or HbA1c levels (P=0.20) in the intervention group. Conclusion: According to the study's findings, vitamin D addition has improved plasma vitamin D3 levels and improved insulin sensitivity in patients with T2DM. The current analysis did not find a significant contribution to reducing HbA1c or enhancing glycemic control in individuals with T2DM. https://journal.afmdc.edu.pk/index.php/AFMDC/article/view/295Vitamin DType 2 Diabetes mellitusFasting Blood sugar |
| spellingShingle | Rabab Zehra Zareen Naz Samina Mohyuddin Saima Zainab Aarfa Amjad Ittafaq Hussain Effect of Vitamin D on Fasting Blood Sugar and HbA1c in Type 2 Diabetes Mellitus Patients Journal of Aziz Fatimah Medical and Dental College Vitamin D Type 2 Diabetes mellitus Fasting Blood sugar |
| title | Effect of Vitamin D on Fasting Blood Sugar and HbA1c in Type 2 Diabetes Mellitus Patients |
| title_full | Effect of Vitamin D on Fasting Blood Sugar and HbA1c in Type 2 Diabetes Mellitus Patients |
| title_fullStr | Effect of Vitamin D on Fasting Blood Sugar and HbA1c in Type 2 Diabetes Mellitus Patients |
| title_full_unstemmed | Effect of Vitamin D on Fasting Blood Sugar and HbA1c in Type 2 Diabetes Mellitus Patients |
| title_short | Effect of Vitamin D on Fasting Blood Sugar and HbA1c in Type 2 Diabetes Mellitus Patients |
| title_sort | effect of vitamin d on fasting blood sugar and hba1c in type 2 diabetes mellitus patients |
| topic | Vitamin D Type 2 Diabetes mellitus Fasting Blood sugar |
| url | https://journal.afmdc.edu.pk/index.php/AFMDC/article/view/295 |
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