Non-invasive colorectal cancer biomarkers: HAND2 and GPM6A methylation in circulating tumour DNA

Non-invasive colorectal cancer biomarkers: HAND2 and GPM6A methylation in circulating tumour DNA

Abstract Background Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Early detection is critical for improving patient outcomes. This study investigated the potential of circulating tumour DNA (ctDNA) methylation markers, specifically Heart and Neural Crest Derivatives...

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Bibliographic Details
Main Authors: Amir Mahdi Nili, Kamal Mohammadian, Fatemeh Namazi Nanehkaran, Faranak Jamshidian, Arash Moradi, Shahla Mohammad Ganji
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cancer Cell International
Subjects:
Colorectal cancer
Non-invasive biomarker
CtDNA
GPM6A
HAND2
Online Access:https://doi.org/10.1186/s12935-025-03898-5
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