Precursor B-cell lymphoblastic lymphoma of bone in children: A close mimicker of Ewing's sarcoma
Precursor B-cell lymphoblastic lymphoma (LBL) occurring as a primary bone tumor is a rare clinical presentation in children, and data regarding this condition are limited to small case series or a few individual case reports. We report two pediatric cases of precursor B-cell LBL of the bone. The tum...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2018-01-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| Online Access: | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2018;volume=39;issue=3;spage=385;epage=387;aulast=Seetharam |
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| author | Shwetha Seetharam Priyakumari Thankamony Priya Mary Jacob Rekha Appukuttan Nair |
| author_facet | Shwetha Seetharam Priyakumari Thankamony Priya Mary Jacob Rekha Appukuttan Nair |
| author_sort | Shwetha Seetharam |
| collection | DOAJ |
| description | Precursor B-cell lymphoblastic lymphoma (LBL) occurring as a primary bone tumor is a rare clinical presentation in children, and data regarding this condition are limited to small case series or a few individual case reports. We report two pediatric cases of precursor B-cell LBL of the bone. The tumor cells from bone biopsies of both patients were seen to be positive for leukocyte common antigen (LCA), terminal deoxynucleotidyl transferase, CD10, CD20 and weakly positive for CD99. Bone marrow studies were normal. They were treated according to the modified Berlin-Frankfurt-Münster acute lymphoblastic leukemia high-risk protocol. The first patient has completed treatment including local radiotherapy and has been disease free for the past 10 years. The second patient has recently completed treatment and shows good response. |
| format | Article |
| id | doaj-art-7e7c6cd860b441f09aec27ec8bde011b |
| institution | DOAJ |
| issn | 0971-5851 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-7e7c6cd860b441f09aec27ec8bde011b2025-08-20T03:04:01ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512018-01-0139338538710.4103/ijmpo.ijmpo_149_16Precursor B-cell lymphoblastic lymphoma of bone in children: A close mimicker of Ewing's sarcomaShwetha SeetharamPriyakumari ThankamonyPriya Mary JacobRekha Appukuttan NairPrecursor B-cell lymphoblastic lymphoma (LBL) occurring as a primary bone tumor is a rare clinical presentation in children, and data regarding this condition are limited to small case series or a few individual case reports. We report two pediatric cases of precursor B-cell LBL of the bone. The tumor cells from bone biopsies of both patients were seen to be positive for leukocyte common antigen (LCA), terminal deoxynucleotidyl transferase, CD10, CD20 and weakly positive for CD99. Bone marrow studies were normal. They were treated according to the modified Berlin-Frankfurt-Münster acute lymphoblastic leukemia high-risk protocol. The first patient has completed treatment including local radiotherapy and has been disease free for the past 10 years. The second patient has recently completed treatment and shows good response.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2018;volume=39;issue=3;spage=385;epage=387;aulast=SeetharamBone tumorslymphoblastic lymphomapediatric oncologyprimary bone lymphoma |
| spellingShingle | Shwetha Seetharam Priyakumari Thankamony Priya Mary Jacob Rekha Appukuttan Nair Precursor B-cell lymphoblastic lymphoma of bone in children: A close mimicker of Ewing's sarcoma Indian Journal of Medical and Paediatric Oncology Bone tumors lymphoblastic lymphoma pediatric oncology primary bone lymphoma |
| title | Precursor B-cell lymphoblastic lymphoma of bone in children: A close mimicker of Ewing's sarcoma |
| title_full | Precursor B-cell lymphoblastic lymphoma of bone in children: A close mimicker of Ewing's sarcoma |
| title_fullStr | Precursor B-cell lymphoblastic lymphoma of bone in children: A close mimicker of Ewing's sarcoma |
| title_full_unstemmed | Precursor B-cell lymphoblastic lymphoma of bone in children: A close mimicker of Ewing's sarcoma |
| title_short | Precursor B-cell lymphoblastic lymphoma of bone in children: A close mimicker of Ewing's sarcoma |
| title_sort | precursor b cell lymphoblastic lymphoma of bone in children a close mimicker of ewing s sarcoma |
| topic | Bone tumors lymphoblastic lymphoma pediatric oncology primary bone lymphoma |
| url | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2018;volume=39;issue=3;spage=385;epage=387;aulast=Seetharam |
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