On Neuropsychiatric Manifestations of Basal Ganglia Injury: A Report of Three Cases and Literature Review
The basal ganglia have been considered to primarily play a role in motor processing. A growing body of theoretical and clinical evidence shows that in addition to the motor functions the basal ganglia play a key role in perceptual and visual disturbances. This role may be evident in patients with ba...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2019/3298791 |
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| author | Heela Azizi Alexander Kilpatrick Olaniyi Olayinka Olusegun Poopola Maleeha Ahmad Alexa Kahn Tasmia Khan Dina Rimawi Shantale Williams Sinthuja Jayaraj Ivan Leung Sherina Langdon Mirna Iskander Ali Chohan Deepa Nuthalapati Ulunma Umesi Geetha Vyas Ayotomide Oyelakin Kodjovi Kodjo Chiedozie Ojimba Oluwole Jegede Carolina Nisenoff Ayodeji Jolayemi |
| author_facet | Heela Azizi Alexander Kilpatrick Olaniyi Olayinka Olusegun Poopola Maleeha Ahmad Alexa Kahn Tasmia Khan Dina Rimawi Shantale Williams Sinthuja Jayaraj Ivan Leung Sherina Langdon Mirna Iskander Ali Chohan Deepa Nuthalapati Ulunma Umesi Geetha Vyas Ayotomide Oyelakin Kodjovi Kodjo Chiedozie Ojimba Oluwole Jegede Carolina Nisenoff Ayodeji Jolayemi |
| author_sort | Heela Azizi |
| collection | DOAJ |
| description | The basal ganglia have been considered to primarily play a role in motor processing. A growing body of theoretical and clinical evidence shows that in addition to the motor functions the basal ganglia play a key role in perceptual and visual disturbances. This role may be evident in patients with basal ganglia pathology and subsequent manifestation of symptoms that include cognitive, perceptual, and affective disturbances. We present three cases with basal ganglia pathology that demonstrate affective and psychotic symptoms. Two of the cases presented with late onset psychotic disturbances suggesting likely neurological etiologies. The third case presented with treatment refractory psychosis and symptoms that are rare for a diagnosis of schizophrenia. The role of incidental bilateral basal ganglia calcifications in all the cases is discussed. A review of current literature highlighting various neuropsychiatric manifestations of basal ganglia pathologies in various patients with psychiatric symptoms is presented. |
| format | Article |
| id | doaj-art-7e70f1a2bb09484ab86c1ce11753ae6a |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-7e70f1a2bb09484ab86c1ce11753ae6a2025-08-20T03:35:34ZengWileyCase Reports in Neurological Medicine2090-66682090-66762019-01-01201910.1155/2019/32987913298791On Neuropsychiatric Manifestations of Basal Ganglia Injury: A Report of Three Cases and Literature ReviewHeela Azizi0Alexander Kilpatrick1Olaniyi Olayinka2Olusegun Poopola3Maleeha Ahmad4Alexa Kahn5Tasmia Khan6Dina Rimawi7Shantale Williams8Sinthuja Jayaraj9Ivan Leung10Sherina Langdon11Mirna Iskander12Ali Chohan13Deepa Nuthalapati14Ulunma Umesi15Geetha Vyas16Ayotomide Oyelakin17Kodjovi Kodjo18Chiedozie Ojimba19Oluwole Jegede20Carolina Nisenoff21Ayodeji Jolayemi22American University of Antigua College of Medicine, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAAmerican University of Antigua College of Medicine, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAAmerican University of Antigua College of Medicine, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAAmerican University of Antigua College of Medicine, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAMedical University of the Americas, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAAmerican University of Antigua College of Medicine, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAAmerican University of Antigua College of Medicine, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAAmerican University of Antigua College of Medicine, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USASaba University School of Medicine, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAAmerican University of Antigua College of Medicine, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAAmerican University of Antigua College of Medicine, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAAmerican University of Antigua College of Medicine, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAAmerican University of Antigua College of Medicine, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAMedical University of the Americas, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAAmerican University of Antigua College of Medicine, Department of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, New York, USAThe basal ganglia have been considered to primarily play a role in motor processing. A growing body of theoretical and clinical evidence shows that in addition to the motor functions the basal ganglia play a key role in perceptual and visual disturbances. This role may be evident in patients with basal ganglia pathology and subsequent manifestation of symptoms that include cognitive, perceptual, and affective disturbances. We present three cases with basal ganglia pathology that demonstrate affective and psychotic symptoms. Two of the cases presented with late onset psychotic disturbances suggesting likely neurological etiologies. The third case presented with treatment refractory psychosis and symptoms that are rare for a diagnosis of schizophrenia. The role of incidental bilateral basal ganglia calcifications in all the cases is discussed. A review of current literature highlighting various neuropsychiatric manifestations of basal ganglia pathologies in various patients with psychiatric symptoms is presented.http://dx.doi.org/10.1155/2019/3298791 |
| spellingShingle | Heela Azizi Alexander Kilpatrick Olaniyi Olayinka Olusegun Poopola Maleeha Ahmad Alexa Kahn Tasmia Khan Dina Rimawi Shantale Williams Sinthuja Jayaraj Ivan Leung Sherina Langdon Mirna Iskander Ali Chohan Deepa Nuthalapati Ulunma Umesi Geetha Vyas Ayotomide Oyelakin Kodjovi Kodjo Chiedozie Ojimba Oluwole Jegede Carolina Nisenoff Ayodeji Jolayemi On Neuropsychiatric Manifestations of Basal Ganglia Injury: A Report of Three Cases and Literature Review Case Reports in Neurological Medicine |
| title | On Neuropsychiatric Manifestations of Basal Ganglia Injury: A Report of Three Cases and Literature Review |
| title_full | On Neuropsychiatric Manifestations of Basal Ganglia Injury: A Report of Three Cases and Literature Review |
| title_fullStr | On Neuropsychiatric Manifestations of Basal Ganglia Injury: A Report of Three Cases and Literature Review |
| title_full_unstemmed | On Neuropsychiatric Manifestations of Basal Ganglia Injury: A Report of Three Cases and Literature Review |
| title_short | On Neuropsychiatric Manifestations of Basal Ganglia Injury: A Report of Three Cases and Literature Review |
| title_sort | on neuropsychiatric manifestations of basal ganglia injury a report of three cases and literature review |
| url | http://dx.doi.org/10.1155/2019/3298791 |
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