STATUS OF PAIR LYMPH NODES IN MICE WITH SPONTANEOUS TUMORS OF HEMATOPOETIC SYSTEM
An asymmetry of renal lymph nodes involvement has been found in laboratory mice (BALB/c) with spontaneous blood neoplasms (lymphomas and leukemias). Left lymph node is more frequently involved and its enlargement (lymphadenopathy) is significantly more expressive in compare to right lymph node. The...
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Russian Academy of Sciences, Tomsk National Research Medical Center
2016-02-01
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| Series: | Сибирский онкологический журнал |
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| Online Access: | https://www.siboncoj.ru/jour/article/view/28 |
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| author | V. N. Manskikh |
| author_facet | V. N. Manskikh |
| author_sort | V. N. Manskikh |
| collection | DOAJ |
| description | An asymmetry of renal lymph nodes involvement has been found in laboratory mice (BALB/c) with spontaneous blood neoplasms (lymphomas and leukemias). Left lymph node is more frequently involved and its enlargement (lymphadenopathy) is significantly more expressive in compare to right lymph node. The difference is not related to sex of animals and histological type of neoplasm. Microscopic pictures of the affected right and left lymph nodes also do not demonstrate differences. The involvement of other pair lymph nodes is not shown to be asymmetrical constantly. It seems that the asymmetry of renal lymph nodes involvement is related to more intensive glucocorticoids production by right adrenal gland in compare to left adrenal gland, consequently, higher level of antiproliferative adrenal hormones in lymph which drain from adrenal glands to ipsilateral lymph nodes. |
| format | Article |
| id | doaj-art-7e6efa26ef894d8c8186252d55ca093e |
| institution | DOAJ |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| publishDate | 2016-02-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj-art-7e6efa26ef894d8c8186252d55ca093e2025-08-20T02:59:11ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682016-02-0102283028STATUS OF PAIR LYMPH NODES IN MICE WITH SPONTANEOUS TUMORS OF HEMATOPOETIC SYSTEMV. N. Manskikh0M.V. Lomonosov Moscow State University, MoscowAn asymmetry of renal lymph nodes involvement has been found in laboratory mice (BALB/c) with spontaneous blood neoplasms (lymphomas and leukemias). Left lymph node is more frequently involved and its enlargement (lymphadenopathy) is significantly more expressive in compare to right lymph node. The difference is not related to sex of animals and histological type of neoplasm. Microscopic pictures of the affected right and left lymph nodes also do not demonstrate differences. The involvement of other pair lymph nodes is not shown to be asymmetrical constantly. It seems that the asymmetry of renal lymph nodes involvement is related to more intensive glucocorticoids production by right adrenal gland in compare to left adrenal gland, consequently, higher level of antiproliferative adrenal hormones in lymph which drain from adrenal glands to ipsilateral lymph nodes.https://www.siboncoj.ru/jour/article/view/28spontaneous lymphomas in micefunctional asymmetryrenal lymph nodes |
| spellingShingle | V. N. Manskikh STATUS OF PAIR LYMPH NODES IN MICE WITH SPONTANEOUS TUMORS OF HEMATOPOETIC SYSTEM Сибирский онкологический журнал spontaneous lymphomas in mice functional asymmetry renal lymph nodes |
| title | STATUS OF PAIR LYMPH NODES IN MICE WITH SPONTANEOUS TUMORS OF HEMATOPOETIC SYSTEM |
| title_full | STATUS OF PAIR LYMPH NODES IN MICE WITH SPONTANEOUS TUMORS OF HEMATOPOETIC SYSTEM |
| title_fullStr | STATUS OF PAIR LYMPH NODES IN MICE WITH SPONTANEOUS TUMORS OF HEMATOPOETIC SYSTEM |
| title_full_unstemmed | STATUS OF PAIR LYMPH NODES IN MICE WITH SPONTANEOUS TUMORS OF HEMATOPOETIC SYSTEM |
| title_short | STATUS OF PAIR LYMPH NODES IN MICE WITH SPONTANEOUS TUMORS OF HEMATOPOETIC SYSTEM |
| title_sort | status of pair lymph nodes in mice with spontaneous tumors of hematopoetic system |
| topic | spontaneous lymphomas in mice functional asymmetry renal lymph nodes |
| url | https://www.siboncoj.ru/jour/article/view/28 |
| work_keys_str_mv | AT vnmanskikh statusofpairlymphnodesinmicewithspontaneoustumorsofhematopoeticsystem |