Machine learning–enhanced screening funnel for clinical trials in Alzheimer's disease

Abstract INTRODUCTION Alzheimer's disease (AD) clinical trials with therapeutic interventions require hundreds of subjects to be studied over many months/years due to variable and slow disease progression. This article presents a novel screening paradigm integrating disease progression models t...

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Bibliographic Details
Main Authors: Scott Gladstein, Liuqing Yang, Dustin Wooten, Xin Huang, Robert Comley, Qi Guo, the Alzheimer's Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
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Online Access:https://doi.org/10.1002/trc2.70084
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