TWIST1 regulates HK2 ubiquitination degradation to promote pancreatic cancer invasion and metastasis

Abstract Objective TWIST1 is known to promote glycolysis and contribute to pancreatic cancer development; however, its underlying mechanisms remain poorly understood. This study aims to elucidate the molecular mechanisms by which TWIST1 influences aerobic glycolysis in pancreatic ductal adenocarcino...

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Bibliographic Details
Main Authors: Xinxing Wang, Mingze Ma, Shuai Shao, Xianwen Xu, Chuan Qin, Ruxin Gao, Zhenhai Zhang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Cancer Cell International
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Online Access:https://doi.org/10.1186/s12935-024-03583-z
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