Analysis of phosphomotifs coupled to phosphoproteome and interactome unveils potential human kinase substrate proteins in SARS-CoV-2

Analysis of phosphomotifs coupled to phosphoproteome and interactome unveils potential human kinase substrate proteins in SARS-CoV-2

IntroductionViruses exploit host kinases to phosphorylate their proteins, enabling viral replication and interference with host-cell functions. Understanding phosphorylation in SARS-CoV-2 proteins necessitates identifying viral phosphoproteins, their phosphosites, and the host kinase–viral protein i...

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Bibliographic Details
Main Authors: Vineetha Shaji, Ahmad Rafi, Mukhtar Ahmed, Athira Perunelly Gopalakrishnan, Sowmya Soman, Amjesh Revikumar, Ganesh Prasad, Abhithaj Jayanandan, Rajesh Raju
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
phosphorylation
SARS-CoV-2
human kinase substrate motifs
human-viral protein-protein interactome
viral phosphosites
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1554760/full
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