Desktop Software for Patch-Clamp Raw Binary Data Conversion and Preprocessing
Since raw data recorded by patch-clamp systems are always stored in binary format, electrophysiologists may experience difficulties with patch clamp data preprocessing especially when they want to analyze by custom-designed algorithms. In this study, we present desktop software, called PCDReader, wh...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | Journal of Electrical and Computer Engineering |
| Online Access: | http://dx.doi.org/10.1155/2011/251215 |
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| _version_ | 1850214299918663680 |
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| author | Ning Zhang Yutao Tian Lei Zhang Zhuo Yang Tao Zhang Jishou Ruan |
| author_facet | Ning Zhang Yutao Tian Lei Zhang Zhuo Yang Tao Zhang Jishou Ruan |
| author_sort | Ning Zhang |
| collection | DOAJ |
| description | Since raw data recorded by patch-clamp systems are always stored in binary format, electrophysiologists may experience difficulties with patch clamp data preprocessing especially when they want to analyze by custom-designed algorithms. In this study, we present desktop software, called PCDReader, which could be an effective and convenient solution for patch clamp data preprocessing for daily laboratory use. We designed a novel class module, called clsPulseData, to directly read the raw data along with the parameters recorded from HEKA instruments without any other program support. By a graphical user interface, raw binary data files can be converted into several kinds of ASCII text files for further analysis, with several preprocessing options. And the parameters can also be viewed, modified and exported into ASCII files by a user-friendly Explorer style window. The real-time data loading technique and optimized memory management programming makes PCDReader a fast and efficient tool. The compiled software along with the source code of the clsPulseData class module is freely available to academic and nonprofit users. |
| format | Article |
| id | doaj-art-7e58a4d236264d5a89a434c82dc70b73 |
| institution | OA Journals |
| issn | 2090-0147 2090-0155 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Electrical and Computer Engineering |
| spelling | doaj-art-7e58a4d236264d5a89a434c82dc70b732025-08-20T02:08:57ZengWileyJournal of Electrical and Computer Engineering2090-01472090-01552011-01-01201110.1155/2011/251215251215Desktop Software for Patch-Clamp Raw Binary Data Conversion and PreprocessingNing Zhang0Yutao Tian1Lei Zhang2Zhuo Yang3Tao Zhang4Jishou Ruan5Chern Institute of Mathematics and College of Mathematical Science, Nankai University, Tianjin 300071, ChinaKey Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, ChinaKey Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, ChinaKey Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, ChinaKey Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, ChinaChern Institute of Mathematics and College of Mathematical Science, Nankai University, Tianjin 300071, ChinaSince raw data recorded by patch-clamp systems are always stored in binary format, electrophysiologists may experience difficulties with patch clamp data preprocessing especially when they want to analyze by custom-designed algorithms. In this study, we present desktop software, called PCDReader, which could be an effective and convenient solution for patch clamp data preprocessing for daily laboratory use. We designed a novel class module, called clsPulseData, to directly read the raw data along with the parameters recorded from HEKA instruments without any other program support. By a graphical user interface, raw binary data files can be converted into several kinds of ASCII text files for further analysis, with several preprocessing options. And the parameters can also be viewed, modified and exported into ASCII files by a user-friendly Explorer style window. The real-time data loading technique and optimized memory management programming makes PCDReader a fast and efficient tool. The compiled software along with the source code of the clsPulseData class module is freely available to academic and nonprofit users.http://dx.doi.org/10.1155/2011/251215 |
| spellingShingle | Ning Zhang Yutao Tian Lei Zhang Zhuo Yang Tao Zhang Jishou Ruan Desktop Software for Patch-Clamp Raw Binary Data Conversion and Preprocessing Journal of Electrical and Computer Engineering |
| title | Desktop Software for Patch-Clamp Raw Binary Data Conversion and Preprocessing |
| title_full | Desktop Software for Patch-Clamp Raw Binary Data Conversion and Preprocessing |
| title_fullStr | Desktop Software for Patch-Clamp Raw Binary Data Conversion and Preprocessing |
| title_full_unstemmed | Desktop Software for Patch-Clamp Raw Binary Data Conversion and Preprocessing |
| title_short | Desktop Software for Patch-Clamp Raw Binary Data Conversion and Preprocessing |
| title_sort | desktop software for patch clamp raw binary data conversion and preprocessing |
| url | http://dx.doi.org/10.1155/2011/251215 |
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