Dietary iron oxide (Fe2O3) nanoparticles modulate growth performance, body composition, mineral content and intestinal health of yellow catfish juveniles (Pelteobagrus fulvidraco)
The present study investigated the growth performance, body composition, mineral content and intestinal health of yellow catfish juveniles fed different iron diets and explored the dietary Fe requirements for this fish species. Using iron oxide nanoparticles (Fe2O3 NPs) as the Fe sources, we formula...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-07-01
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| Series: | Aquaculture Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352513425001255 |
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| Summary: | The present study investigated the growth performance, body composition, mineral content and intestinal health of yellow catfish juveniles fed different iron diets and explored the dietary Fe requirements for this fish species. Using iron oxide nanoparticles (Fe2O3 NPs) as the Fe sources, we formulated six experimental diets with dietary Fe levels at 22.23, 28.28, 36.10, 44.53, 52.21, and 61.85 mg Fe/kg diet, respectively. Yellow catfish fed with 44.53 mg Fe/kg diet had the highest growth performance and feed utilization, while those fed 61.85 mg Fe/kg diet showed the lowest growth performance and feed utilization. Dietary Fe addition increased whole-body and intestinal Fe contents. Additionally, the addition of dietary Fe had an impact on whole-body crude protein, crude lipid, ash, calcium (Ca), magnesium (Mg), zinc (Zn), and manganese (Mn) contents, but did not whole-body moisture and copper (Cu) contents. Yellow catfish fed with 44.53 mg Fe/kg diet had an improvement in intestinal histology and an increase in expression of intestinal tight junction-related genes [occludin and tight junction protein 1b (zo-1b)] as well as antioxidant response genes [superoxide dismutase 1 (sod1), sod2 and catalase (cat)], and had higher activities of antioxidant enzymes [CAT, total SOD (T-SOD) and total antioxidant capacity (T-AOC)]. However, malondialdehyde (MDA) content, and gene expression of glucose-regulated protein 78 (grp78), eukaryotic translation initiation factor 2α (eif2α), activating transcription factor 4 (atf4), inositol-requiring enzyme 1 (ire1) (related to endoplasmic reticulum stress), and mRNA levels of tumor necrosis factor α (tnfα), interleukin 1β (il1β), il8 (related to inflammatory response) in the intestine were the lowest in 44.53 mg Fe/kg diet group. Conducting broken-line analysis of weight gain (WG) against dietary Fe levels, we revealed that the optimal Fe requirement was 45.28 mg Fe/kg diet, with Fe2O3 NPs as Fe source. |
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| ISSN: | 2352-5134 |