One-Pot Synthesis and <i>In Vitro</i> Studies of Calix[4]-2-methylresorcinarene Derivatives as Antimalarial Agents Against <i>Plasmodium falciparum</i> Chloroquine-Resistant Strain FCR-3

One-Pot Synthesis and <i>In Vitro</i> Studies of Calix[4]-2-methylresorcinarene Derivatives as Antimalarial Agents Against <i>Plasmodium falciparum</i> Chloroquine-Resistant Strain FCR-3

Malaria is an endemic disease in Indonesia caused by infection from the Plasmodium parasite. Recently, antimalarial resistance significantly contributed to the decline in the cure rate of malaria sufferers. In this work, three calix[4]resorcinarenes have been synthesized from 2-methylresorcinol and...

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Bibliographic Details
Main Authors: Baiq Ike Nursofia, Yehezkiel Steven Kurniawan, Jumina Jumina, Harno Dwi Pranowo, Eti Nurwening Sholikhah, Jeffry Julianus, Susalit Setya Wibowo, Hana Anisa Fatimi, Yoga Priastomo, Krisfian Tata Aneka Priyangga
Format: Article
Language:English
Published: Department of Chemistry, Universitas Gadjah Mada 2024-12-01
Series:Indonesian Journal of Chemistry
Subjects:
antimalarial
calix[4]-2-methylresorcinarene
in vitro assay
one-pot synthesis
plasmodium falciparum
Online Access:https://jurnal.ugm.ac.id/ijc/article/view/94885
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