Longitudinal associations between amyloid and symptoms of depression and anxiety in subjective cognitive decline: the impact of personality characteristics

Longitudinal associations between amyloid and symptoms of depression and anxiety in subjective cognitive decline: the impact of personality characteristics

IntroductionDepressive/anxiety symptoms are common in subjective cognitive decline (SCD) and may relate to Alzheimer’s pathology, potentially modulated by personality characteristics.MethodsDepressive/anxiety symptoms were assessed over 4 ± 2 years in 329 SCD (88 amyloid-positive/241 amyloid-negativ...

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Main Authors: Calvin Trieu, Mardou S. S. A. van Leeuwenstijn, Lisa-Marie Schlüter, Jarith L. Ebenau, Inge M. W. Verberk, Sietske A. M. Sikkes, Sander C. J. Verfaillie, Elsmarieke van de Giessen, Charlotte E. Teunissen, Wiesje M. van der Flier, Argonde C. van Harten
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Psychiatry
Subjects:
Alzheimer’s disease
depression
anxiety
subjective cognitive decline
neuroticism
somatization
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1572174/full
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