Predicting the molecular subtypes of 2021 WHO grade 4 glioma by a multiparametric MRI-based machine learning model

Predicting the molecular subtypes of 2021 WHO grade 4 glioma by a multiparametric MRI-based machine learning model

Abstract Background Accurately distinguishing the different molecular subtypes of 2021 World Health Organization (WHO) grade 4 Central Nervous System (CNS) gliomas is highly relevant for prognostic stratification and personalized treatment. Objectives To develop and validate a machine learning (ML)...

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Bibliographic Details
Main Authors: Wenji Xu, Yangyang Li, Jie Zhang, Zhiyi Zhang, Pengxin Shen, Xiaochun Wang, Guoqiang Yang, Jiangfeng Du, Hui Zhang, Yan Tan
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
Subjects:
Astrocytoma
Glioblastoma
Magnetic resonance imaging
Machine learning
Molecular subtype
Online Access:https://doi.org/10.1186/s12885-025-14529-7
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