A Case of Canine Sinonasal Aspergillus fumigatus Infection Associated With Intracranial Extension and Temporal Myositis
ABSTRACT A 12‐year‐old terrier was referred for investigation of a 4‐month history of coughing, sneezing and nasal discharge. Clinical findings were consistent with sinonasal Aspergillus fumigatus infection with evidence of intracranial extension on computed tomography. Endoscopic debridement follow...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Veterinary Medicine and Science |
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| Online Access: | https://doi.org/10.1002/vms3.70188 |
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| author | Sarah E. Cox Giulia Cattaneo Oliver Russell Ombeline McGregor Andre Kortum |
| author_facet | Sarah E. Cox Giulia Cattaneo Oliver Russell Ombeline McGregor Andre Kortum |
| author_sort | Sarah E. Cox |
| collection | DOAJ |
| description | ABSTRACT A 12‐year‐old terrier was referred for investigation of a 4‐month history of coughing, sneezing and nasal discharge. Clinical findings were consistent with sinonasal Aspergillus fumigatus infection with evidence of intracranial extension on computed tomography. Endoscopic debridement followed by topical clotrimazole and systemic antifungal therapy resulted in clinical improvement. Magnetic resonance imaging after 4 weeks showed reduced intracranial disease but demonstrated evidence of temporal myositis. Repeated debridement and topical treatment were performed at 4 and 8 weeks in conjunction with long‐term voriconazole therapy. Further interventions were declined; the dog remains clinically well after 4 months with unilateral nasal discharge. As in human patients, invasive subtypes of sinonasal aspergillosis may also occur in dogs and be associated with poorer response to treatment. |
| format | Article |
| id | doaj-art-7e2e29b8ca9d4f19bb808b436c522a3c |
| institution | DOAJ |
| issn | 2053-1095 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Veterinary Medicine and Science |
| spelling | doaj-art-7e2e29b8ca9d4f19bb808b436c522a3c2025-08-20T02:40:41ZengWileyVeterinary Medicine and Science2053-10952025-01-01111n/an/a10.1002/vms3.70188A Case of Canine Sinonasal Aspergillus fumigatus Infection Associated With Intracranial Extension and Temporal MyositisSarah E. Cox0Giulia Cattaneo1Oliver Russell2Ombeline McGregor3Andre Kortum4Department of Veterinary Medicine University of Cambridge Cambridge UKDepartment of Veterinary Medicine University of Cambridge Cambridge UKDepartment of Veterinary Medicine University of Cambridge Cambridge UKDepartment of Veterinary Medicine University of Cambridge Cambridge UKDepartment of Veterinary Medicine University of Cambridge Cambridge UKABSTRACT A 12‐year‐old terrier was referred for investigation of a 4‐month history of coughing, sneezing and nasal discharge. Clinical findings were consistent with sinonasal Aspergillus fumigatus infection with evidence of intracranial extension on computed tomography. Endoscopic debridement followed by topical clotrimazole and systemic antifungal therapy resulted in clinical improvement. Magnetic resonance imaging after 4 weeks showed reduced intracranial disease but demonstrated evidence of temporal myositis. Repeated debridement and topical treatment were performed at 4 and 8 weeks in conjunction with long‐term voriconazole therapy. Further interventions were declined; the dog remains clinically well after 4 months with unilateral nasal discharge. As in human patients, invasive subtypes of sinonasal aspergillosis may also occur in dogs and be associated with poorer response to treatment.https://doi.org/10.1002/vms3.70188computed tomographyfungalmagnetic resonance imaging |
| spellingShingle | Sarah E. Cox Giulia Cattaneo Oliver Russell Ombeline McGregor Andre Kortum A Case of Canine Sinonasal Aspergillus fumigatus Infection Associated With Intracranial Extension and Temporal Myositis Veterinary Medicine and Science computed tomography fungal magnetic resonance imaging |
| title | A Case of Canine Sinonasal Aspergillus fumigatus Infection Associated With Intracranial Extension and Temporal Myositis |
| title_full | A Case of Canine Sinonasal Aspergillus fumigatus Infection Associated With Intracranial Extension and Temporal Myositis |
| title_fullStr | A Case of Canine Sinonasal Aspergillus fumigatus Infection Associated With Intracranial Extension and Temporal Myositis |
| title_full_unstemmed | A Case of Canine Sinonasal Aspergillus fumigatus Infection Associated With Intracranial Extension and Temporal Myositis |
| title_short | A Case of Canine Sinonasal Aspergillus fumigatus Infection Associated With Intracranial Extension and Temporal Myositis |
| title_sort | case of canine sinonasal aspergillus fumigatus infection associated with intracranial extension and temporal myositis |
| topic | computed tomography fungal magnetic resonance imaging |
| url | https://doi.org/10.1002/vms3.70188 |
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