Lower adenoma detection rate in anesthesia assisted colonoscopy: a retrospective study

ObjectivesAs anesthesia assisted (AA) colonoscopy becomes increasingly popular, there has been concern about its impact on the quality of colonoscopy examinations. We aimed to clarify the impact of anesthesia assistance on the adenoma detection rate (ADR) and non-adenomatous polyp detection rate (PD...

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Main Authors: Chang Cai, Zhihua Xu, Bin Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1571387/full
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author Chang Cai
Zhihua Xu
Bin Ye
author_facet Chang Cai
Zhihua Xu
Bin Ye
author_sort Chang Cai
collection DOAJ
description ObjectivesAs anesthesia assisted (AA) colonoscopy becomes increasingly popular, there has been concern about its impact on the quality of colonoscopy examinations. We aimed to clarify the impact of anesthesia assistance on the adenoma detection rate (ADR) and non-adenomatous polyp detection rate (PDR) of colonoscopy.MethodsWe collected data from patients undergoing colonoscopy throughout the year 2023 at our institution, with a total of 16,465 cases identified for potential analysis. After using propensity score matching (PSM) to minimize the influence of other variables on the study outcomes, there were 6,094 cases remaining for analysis in both the AA group and non-AA group, respectively. Then, we compared the ADR and PDR between the two groups and analyzed the colon location and size of adenomas or polyps found in different groups.ResultsThe ADR in the non-AA group (36.94%) was significantly higher than that in the AA group (26.40%) (p<0.0001), while there was no statistically significant difference in the PDR between the two groups. AA could also affect the probability of discovering adenomas or polyps in some colon segments, but had no significant effect on the size of the discovered adenomas or polyps. In addition, there were more significant advantages of ADR in the non-AA group among the more experienced endoscopists’ cohort.ConclusionsNon-AA colonoscopy had a higher ADR, suggesting that while AA may potentially reduce patient stress responses to some extent, it confers few benefits in terms of adenoma detection.Clinical Trial Registrationhttps://www.chictr.org.cn/showproj.html?proj=232248.
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spelling doaj-art-7e25890dfb714832aa25702d1a820df72025-08-20T03:09:07ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-04-011510.3389/fonc.2025.15713871571387Lower adenoma detection rate in anesthesia assisted colonoscopy: a retrospective studyChang CaiZhihua XuBin YeObjectivesAs anesthesia assisted (AA) colonoscopy becomes increasingly popular, there has been concern about its impact on the quality of colonoscopy examinations. We aimed to clarify the impact of anesthesia assistance on the adenoma detection rate (ADR) and non-adenomatous polyp detection rate (PDR) of colonoscopy.MethodsWe collected data from patients undergoing colonoscopy throughout the year 2023 at our institution, with a total of 16,465 cases identified for potential analysis. After using propensity score matching (PSM) to minimize the influence of other variables on the study outcomes, there were 6,094 cases remaining for analysis in both the AA group and non-AA group, respectively. Then, we compared the ADR and PDR between the two groups and analyzed the colon location and size of adenomas or polyps found in different groups.ResultsThe ADR in the non-AA group (36.94%) was significantly higher than that in the AA group (26.40%) (p<0.0001), while there was no statistically significant difference in the PDR between the two groups. AA could also affect the probability of discovering adenomas or polyps in some colon segments, but had no significant effect on the size of the discovered adenomas or polyps. In addition, there were more significant advantages of ADR in the non-AA group among the more experienced endoscopists’ cohort.ConclusionsNon-AA colonoscopy had a higher ADR, suggesting that while AA may potentially reduce patient stress responses to some extent, it confers few benefits in terms of adenoma detection.Clinical Trial Registrationhttps://www.chictr.org.cn/showproj.html?proj=232248.https://www.frontiersin.org/articles/10.3389/fonc.2025.1571387/fullcolonoscopyendoscopyanesthesia assistanceADRPDR
spellingShingle Chang Cai
Zhihua Xu
Bin Ye
Lower adenoma detection rate in anesthesia assisted colonoscopy: a retrospective study
Frontiers in Oncology
colonoscopy
endoscopy
anesthesia assistance
ADR
PDR
title Lower adenoma detection rate in anesthesia assisted colonoscopy: a retrospective study
title_full Lower adenoma detection rate in anesthesia assisted colonoscopy: a retrospective study
title_fullStr Lower adenoma detection rate in anesthesia assisted colonoscopy: a retrospective study
title_full_unstemmed Lower adenoma detection rate in anesthesia assisted colonoscopy: a retrospective study
title_short Lower adenoma detection rate in anesthesia assisted colonoscopy: a retrospective study
title_sort lower adenoma detection rate in anesthesia assisted colonoscopy a retrospective study
topic colonoscopy
endoscopy
anesthesia assistance
ADR
PDR
url https://www.frontiersin.org/articles/10.3389/fonc.2025.1571387/full
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AT zhihuaxu loweradenomadetectionrateinanesthesiaassistedcolonoscopyaretrospectivestudy
AT binye loweradenomadetectionrateinanesthesiaassistedcolonoscopyaretrospectivestudy