Diagnostic Workup for Disorders of Bone and Mineral Metabolism in Patients with Chronic Kidney Disease in the Era of KDIGO Guidelines

KDIGO (Kidney Disease: Improving Global Outcomes) is an international nonprofit organization devoted to “improve the care and outcomes of kidney disease patients worldwide through promoting coordination, collaboration, and integration of initiatives to develop and implement clinical practice guideli...

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Main Authors: Luigi Francesco Morrone, Domenico Russo, Biagio Di Iorio
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:International Journal of Nephrology
Online Access:http://dx.doi.org/10.4061/2011/958798
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author Luigi Francesco Morrone
Domenico Russo
Biagio Di Iorio
author_facet Luigi Francesco Morrone
Domenico Russo
Biagio Di Iorio
author_sort Luigi Francesco Morrone
collection DOAJ
description KDIGO (Kidney Disease: Improving Global Outcomes) is an international nonprofit organization devoted to “improve the care and outcomes of kidney disease patients worldwide through promoting coordination, collaboration, and integration of initiatives to develop and implement clinical practice guidelines.” The mineral and bone disorder (MBD) in patients with chronic kidney disease (CKD) has been the first area of interest of KDIGO international initiative. KDIGO guidelines on CKD-MBD were published in 2009 with the intent to modify the previous KDOQI guidelines that had failed to consistently change the global outcome of CKD patients. After the publication of KDOQI guidelines for bone metabolism and disease in 2003, a large number of observational data emerged in literature linking disordered mineral metabolism with adverse clinical outcomes. Notwithstanding this large body of observational data, a paucity of evidence from high-quality clinical trials was available for the development of KDIGO guidelines. Herein, a summary will be provided of the most important findings of KDIGO guidelines regarding the diagnostic workup and clinical monitoring of CKD-MBD patients.
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spelling doaj-art-7e252f4b72b94ef9980f1b389e1bb9a52025-08-20T03:35:33ZengWileyInternational Journal of Nephrology2090-214X2090-21582011-01-01201110.4061/2011/958798958798Diagnostic Workup for Disorders of Bone and Mineral Metabolism in Patients with Chronic Kidney Disease in the Era of KDIGO GuidelinesLuigi Francesco Morrone0Domenico Russo1Biagio Di Iorio2Department of Nephrology and Dialysis, G. Rummo Hospital, 82100 Benevento, ItalyDepartment of Nephrology, School of Medicine, University of Naples Federico II, 80138 Naples, ItalyDepartment of Medicine, SOC of Nephrology, “A. Landolfi” Hospital, 83029 Solofra, ItalyKDIGO (Kidney Disease: Improving Global Outcomes) is an international nonprofit organization devoted to “improve the care and outcomes of kidney disease patients worldwide through promoting coordination, collaboration, and integration of initiatives to develop and implement clinical practice guidelines.” The mineral and bone disorder (MBD) in patients with chronic kidney disease (CKD) has been the first area of interest of KDIGO international initiative. KDIGO guidelines on CKD-MBD were published in 2009 with the intent to modify the previous KDOQI guidelines that had failed to consistently change the global outcome of CKD patients. After the publication of KDOQI guidelines for bone metabolism and disease in 2003, a large number of observational data emerged in literature linking disordered mineral metabolism with adverse clinical outcomes. Notwithstanding this large body of observational data, a paucity of evidence from high-quality clinical trials was available for the development of KDIGO guidelines. Herein, a summary will be provided of the most important findings of KDIGO guidelines regarding the diagnostic workup and clinical monitoring of CKD-MBD patients.http://dx.doi.org/10.4061/2011/958798
spellingShingle Luigi Francesco Morrone
Domenico Russo
Biagio Di Iorio
Diagnostic Workup for Disorders of Bone and Mineral Metabolism in Patients with Chronic Kidney Disease in the Era of KDIGO Guidelines
International Journal of Nephrology
title Diagnostic Workup for Disorders of Bone and Mineral Metabolism in Patients with Chronic Kidney Disease in the Era of KDIGO Guidelines
title_full Diagnostic Workup for Disorders of Bone and Mineral Metabolism in Patients with Chronic Kidney Disease in the Era of KDIGO Guidelines
title_fullStr Diagnostic Workup for Disorders of Bone and Mineral Metabolism in Patients with Chronic Kidney Disease in the Era of KDIGO Guidelines
title_full_unstemmed Diagnostic Workup for Disorders of Bone and Mineral Metabolism in Patients with Chronic Kidney Disease in the Era of KDIGO Guidelines
title_short Diagnostic Workup for Disorders of Bone and Mineral Metabolism in Patients with Chronic Kidney Disease in the Era of KDIGO Guidelines
title_sort diagnostic workup for disorders of bone and mineral metabolism in patients with chronic kidney disease in the era of kdigo guidelines
url http://dx.doi.org/10.4061/2011/958798
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