CircZFR/YTHDF3 axis drives lymph node metastasis in cervical cancer via FASN translation

CircZFR/YTHDF3 axis drives lymph node metastasis in cervical cancer via FASN translation

Abstract Background Lymph node metastasis is a key driver of poor outcomes in cervical cancer. However, the molecular mechanisms of circular RNAs (circRNAs) driving cervical cancer lymph node metastasis remain unclear. Methods We identified circZFR, fatty acid synthase (FASN) and YTH N6-methyladenos...

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Bibliographic Details
Main Authors: Mingyi Zhou, Yan Gao, Yong Zhang, Lian He, Bo Gao, Yue Zhang, Francois X. Claret, George A. Calin, Danbo Wang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Molecular Cancer
Subjects:
Prognostic markers
Lymph node metastasis
YTH N6-methyladenosine RNA binding protein F3 (YTHDF3)
Fatty acid synthase (FASN)
Online Access:https://doi.org/10.1186/s12943-025-02424-5
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