Feasibility of infant cord blood HIV testing for anti-retroviral post-exposure prophylaxis
Background: Many maternity hospitals in developing country settings deliver women who are of unknown HIV status. The main objectives of this study were to evaluate the acceptability of post-partum infant cord blood HIV testing and the subsequent uptake of interventions to prevent mother-to-child tra...
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| Format: | Article |
| Language: | English |
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The Journal of Infection in Developing Countries
2007-12-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/369 |
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| author | Irene W. Inwani Ruth W. Nduati Rachel M. Musoke |
| author_facet | Irene W. Inwani Ruth W. Nduati Rachel M. Musoke |
| author_sort | Irene W. Inwani |
| collection | DOAJ |
| description | Background: Many maternity hospitals in developing country settings deliver women who are of unknown HIV status. The main objectives of this study were to evaluate the acceptability of post-partum infant cord blood HIV testing and the subsequent uptake of interventions to prevent mother-to-child transmission of HIV.
Methodology: This was a cross-sectional study among infants delivered to women of unknown HIV status at the maternity ward of the Kenyatta National hospital, Kenya. At the time of delivery, five milliliters of cord blood was collected from consecutive singleton-birth infants born to women with unknown HIV status. After delivery, the women were counseled and consent was sought for HIV antibody testing of the cord blood. Anti-retroviral post-exposure prophylaxis was provided for HIV exposed infants and their mothers counseled on infant feeding.
Results: Overall 220 (87%) of the 253 mothers gave consent for HIV testing. This included 35 (90%) of 40 mothers of babies with HIV positive cord blood and 184 (86.4%) of 213 with HIV negative cord blood. Seventeen (48.6%) of the 35 women who knew their status accepted to administer anti-retroviral prophylaxis to their infants, and 28 (80%) chose to breast-feed their infants.
Conclusions: Infant cord blood testing is highly acceptable among women who deliver with an unknown HIV status and provides an additional entry point for prevention of mother-to-child transmission of HIV. |
| format | Article |
| id | doaj-art-7e1abc128de049fea574d9aa8b964e71 |
| institution | Kabale University |
| issn | 1972-2680 |
| language | English |
| publishDate | 2007-12-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-7e1abc128de049fea574d9aa8b964e712025-08-20T03:48:58ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802007-12-0110310.3855/jidc.369Feasibility of infant cord blood HIV testing for anti-retroviral post-exposure prophylaxisIrene W. Inwani0Ruth W. Nduati1Rachel M. Musoke2Department of Paediatrics, Kenyatta National Hospital, P.O Box 20723, NairobiDepartment of Paediatrics and Child Health, College of Health Sciences, University of Nairobi, PO Box 19676, NairobiDepartment of Paediatrics and Child Health, College of Health Sciences, University of Nairobi, PO Box 19676, NairobiBackground: Many maternity hospitals in developing country settings deliver women who are of unknown HIV status. The main objectives of this study were to evaluate the acceptability of post-partum infant cord blood HIV testing and the subsequent uptake of interventions to prevent mother-to-child transmission of HIV. Methodology: This was a cross-sectional study among infants delivered to women of unknown HIV status at the maternity ward of the Kenyatta National hospital, Kenya. At the time of delivery, five milliliters of cord blood was collected from consecutive singleton-birth infants born to women with unknown HIV status. After delivery, the women were counseled and consent was sought for HIV antibody testing of the cord blood. Anti-retroviral post-exposure prophylaxis was provided for HIV exposed infants and their mothers counseled on infant feeding. Results: Overall 220 (87%) of the 253 mothers gave consent for HIV testing. This included 35 (90%) of 40 mothers of babies with HIV positive cord blood and 184 (86.4%) of 213 with HIV negative cord blood. Seventeen (48.6%) of the 35 women who knew their status accepted to administer anti-retroviral prophylaxis to their infants, and 28 (80%) chose to breast-feed their infants. Conclusions: Infant cord blood testing is highly acceptable among women who deliver with an unknown HIV status and provides an additional entry point for prevention of mother-to-child transmission of HIV.https://jidc.org/index.php/journal/article/view/369MaternitycordbloodHIVtesting |
| spellingShingle | Irene W. Inwani Ruth W. Nduati Rachel M. Musoke Feasibility of infant cord blood HIV testing for anti-retroviral post-exposure prophylaxis Journal of Infection in Developing Countries Maternity cord blood HIV testing |
| title | Feasibility of infant cord blood HIV testing for anti-retroviral post-exposure prophylaxis |
| title_full | Feasibility of infant cord blood HIV testing for anti-retroviral post-exposure prophylaxis |
| title_fullStr | Feasibility of infant cord blood HIV testing for anti-retroviral post-exposure prophylaxis |
| title_full_unstemmed | Feasibility of infant cord blood HIV testing for anti-retroviral post-exposure prophylaxis |
| title_short | Feasibility of infant cord blood HIV testing for anti-retroviral post-exposure prophylaxis |
| title_sort | feasibility of infant cord blood hiv testing for anti retroviral post exposure prophylaxis |
| topic | Maternity cord blood HIV testing |
| url | https://jidc.org/index.php/journal/article/view/369 |
| work_keys_str_mv | AT irenewinwani feasibilityofinfantcordbloodhivtestingforantiretroviralpostexposureprophylaxis AT ruthwnduati feasibilityofinfantcordbloodhivtestingforantiretroviralpostexposureprophylaxis AT rachelmmusoke feasibilityofinfantcordbloodhivtestingforantiretroviralpostexposureprophylaxis |