Investigating the interplay between nucleoid-associated proteins, DNA curvature, and CRISPR elements using comparative genomics.

Many prokaryotic and eukaryotic genomes feature a characteristic periodic signal in distribution of short runs of A or T (A-tracts) phased with the DNA helical period of ∼10-11 bp. Such periodic spacing of A-tracts has been associated with intrinsic DNA curvature. In eukaryotes, this periodicity is...

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Bibliographic Details
Main Authors: Hao Tong, Jan Mrázek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090940&type=printable
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