Reliable HPLC Determination of Aflatoxin M1 in Eggs

Aflatoxin M1 is the foremost metabolite of aflatoxin B1 in humans and animals, which may be present in animal products from animals fed with aflatoxin B1 contaminated feed. In this study a high performance liquid chromatography method for determination of aflatoxin M1 in eggs was described. The egg...

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Main Authors: Mostafa M. H. Khalil, Ahmed M. Gomaa, Ahmed Salem Sebaei
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2013/817091
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author Mostafa M. H. Khalil
Ahmed M. Gomaa
Ahmed Salem Sebaei
author_facet Mostafa M. H. Khalil
Ahmed M. Gomaa
Ahmed Salem Sebaei
author_sort Mostafa M. H. Khalil
collection DOAJ
description Aflatoxin M1 is the foremost metabolite of aflatoxin B1 in humans and animals, which may be present in animal products from animals fed with aflatoxin B1 contaminated feed. In this study a high performance liquid chromatography method for determination of aflatoxin M1 in eggs was described. The egg samples were diluted with warmed water and the toxin was immunoextracted followed by fluorescence detection. The average recovery of aflatoxin M1 at the three different levels 0.05, 0.1, and 0.5 μg/kg varied between 87% and 98%. The method is linear from the limit of quantification 0.05 μg/kg up to 3 μg/kg levels. This method is intended for aflatoxin M1 analyses in eggs simply with minimum toxin lose, excellent recovery, and accurate results with the limit of detection 0.01 μg/kg.
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institution Kabale University
issn 2090-8865
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language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Journal of Analytical Methods in Chemistry
spelling doaj-art-7e159a95d3684a71b201a0610905bbd42025-08-20T03:35:33ZengWileyJournal of Analytical Methods in Chemistry2090-88652090-88732013-01-01201310.1155/2013/817091817091Reliable HPLC Determination of Aflatoxin M1 in EggsMostafa M. H. Khalil0Ahmed M. Gomaa1Ahmed Salem Sebaei2Chemistry Department, Faculty of Science, Ain Shams University, Cairo 11566, EgyptQCAP Laboratory, Agriculture Research Center, Ministry of Agriculture, Giza 12311, EgyptQCAP Laboratory, Agriculture Research Center, Ministry of Agriculture, Giza 12311, EgyptAflatoxin M1 is the foremost metabolite of aflatoxin B1 in humans and animals, which may be present in animal products from animals fed with aflatoxin B1 contaminated feed. In this study a high performance liquid chromatography method for determination of aflatoxin M1 in eggs was described. The egg samples were diluted with warmed water and the toxin was immunoextracted followed by fluorescence detection. The average recovery of aflatoxin M1 at the three different levels 0.05, 0.1, and 0.5 μg/kg varied between 87% and 98%. The method is linear from the limit of quantification 0.05 μg/kg up to 3 μg/kg levels. This method is intended for aflatoxin M1 analyses in eggs simply with minimum toxin lose, excellent recovery, and accurate results with the limit of detection 0.01 μg/kg.http://dx.doi.org/10.1155/2013/817091
spellingShingle Mostafa M. H. Khalil
Ahmed M. Gomaa
Ahmed Salem Sebaei
Reliable HPLC Determination of Aflatoxin M1 in Eggs
Journal of Analytical Methods in Chemistry
title Reliable HPLC Determination of Aflatoxin M1 in Eggs
title_full Reliable HPLC Determination of Aflatoxin M1 in Eggs
title_fullStr Reliable HPLC Determination of Aflatoxin M1 in Eggs
title_full_unstemmed Reliable HPLC Determination of Aflatoxin M1 in Eggs
title_short Reliable HPLC Determination of Aflatoxin M1 in Eggs
title_sort reliable hplc determination of aflatoxin m1 in eggs
url http://dx.doi.org/10.1155/2013/817091
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