Synchronous cervical sympathetic chain schwannoma, parathyroid adenoma and hypofunctional nodular goiter - a case report and literature review

Simultaneously diagnosing cervical sympathetic chain schwannoma, nodular goiter and parathyroid adenoma is a very rare event during clinical practice. We had the opportunity to find this unusual association on a female patient. While nodular goiter and parathyroid adenoma are more common diseases an...

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Main Authors: Flaviu Muresan, Alexandrina-Manuela Muresan, Gabriel-Emil Petre, Iacob Domsa, Vasile Ovidiu Fabian, Olga Hilda Orasan
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Journal of Mind and Medical Sciences
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Online Access:https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1432&context=jmms
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author Flaviu Muresan
Alexandrina-Manuela Muresan
Gabriel-Emil Petre
Iacob Domsa
Vasile Ovidiu Fabian
Olga Hilda Orasan
author_facet Flaviu Muresan
Alexandrina-Manuela Muresan
Gabriel-Emil Petre
Iacob Domsa
Vasile Ovidiu Fabian
Olga Hilda Orasan
author_sort Flaviu Muresan
collection DOAJ
description Simultaneously diagnosing cervical sympathetic chain schwannoma, nodular goiter and parathyroid adenoma is a very rare event during clinical practice. We had the opportunity to find this unusual association on a female patient. While nodular goiter and parathyroid adenoma are more common diseases and easier to diagnose, identifying the etiology of a parapharyngeal space tumor remains a challenge and requires multiple imaging studies such as computed tomography scan, magnetic resonance imaging or angiography. A cervical sympathetic chain schwannoma, a carotid body tumor, a paraganglioma or a vagal schwannoma must be taken into account as possible diagnostic variants. Complaints such as Horner`s syndrome, hoarse voice or dysphagia may suggest a nerve originating tumor, but this is a rare situation. Only the surgical exploration is successful in detecting the tumor origin from the cervical sympathetic chain. Even so, the exact origin of the tumor cannot usually be detected without surgical exploration and removal of the piece or biopsies. Therefore, the pathological report of the specimen (adding or not immunohistochemistry tests) is mandatory to be able to confirm the diagnosis of schwannoma.
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spelling doaj-art-7e0f362f42e44bb6bc760aee434629552025-08-20T03:35:24ZengMDPI AGJournal of Mind and Medical Sciences2392-76742024-04-0111126126610.22543/2392-7674.1432Synchronous cervical sympathetic chain schwannoma, parathyroid adenoma and hypofunctional nodular goiter - a case report and literature reviewFlaviu Muresan0Alexandrina-Manuela Muresan1Gabriel-Emil Petre2Iacob Domsa3Vasile Ovidiu Fabian4Olga Hilda Orasan5Iuliu Hatieganu University of Medicine and Pharmacy, Department of Surgery, Cluj-Napoca, RomaniaCF Hospital, Department of Anesthesia and Intensive Care Unit, Cluj-Napoca, RomaniaIuliu Hatieganu University of Medicine and Pharmacy, Department of Surgery, Cluj-Napoca, RomaniaCF Hospital, Department of Pathology, Cluj-Napoca, RomaniaIuliu Hatieganu University of Medicine and Pharmacy, Department of Surgery, Cluj-Napoca, RomaniaIuliu Hatieganu University of Medicine and Pharmacy, Department of Internal Medicine, CF Hospital, Cluj-Napoca, RomaniaSimultaneously diagnosing cervical sympathetic chain schwannoma, nodular goiter and parathyroid adenoma is a very rare event during clinical practice. We had the opportunity to find this unusual association on a female patient. While nodular goiter and parathyroid adenoma are more common diseases and easier to diagnose, identifying the etiology of a parapharyngeal space tumor remains a challenge and requires multiple imaging studies such as computed tomography scan, magnetic resonance imaging or angiography. A cervical sympathetic chain schwannoma, a carotid body tumor, a paraganglioma or a vagal schwannoma must be taken into account as possible diagnostic variants. Complaints such as Horner`s syndrome, hoarse voice or dysphagia may suggest a nerve originating tumor, but this is a rare situation. Only the surgical exploration is successful in detecting the tumor origin from the cervical sympathetic chain. Even so, the exact origin of the tumor cannot usually be detected without surgical exploration and removal of the piece or biopsies. Therefore, the pathological report of the specimen (adding or not immunohistochemistry tests) is mandatory to be able to confirm the diagnosis of schwannoma.https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1432&context=jmmsparapharyngeal space tumorcarotid body tumorparagangliomacervical sympathetic chain schwannomahorner`s syndromevagal schwannoma
spellingShingle Flaviu Muresan
Alexandrina-Manuela Muresan
Gabriel-Emil Petre
Iacob Domsa
Vasile Ovidiu Fabian
Olga Hilda Orasan
Synchronous cervical sympathetic chain schwannoma, parathyroid adenoma and hypofunctional nodular goiter - a case report and literature review
Journal of Mind and Medical Sciences
parapharyngeal space tumor
carotid body tumor
paraganglioma
cervical sympathetic chain schwannoma
horner`s syndrome
vagal schwannoma
title Synchronous cervical sympathetic chain schwannoma, parathyroid adenoma and hypofunctional nodular goiter - a case report and literature review
title_full Synchronous cervical sympathetic chain schwannoma, parathyroid adenoma and hypofunctional nodular goiter - a case report and literature review
title_fullStr Synchronous cervical sympathetic chain schwannoma, parathyroid adenoma and hypofunctional nodular goiter - a case report and literature review
title_full_unstemmed Synchronous cervical sympathetic chain schwannoma, parathyroid adenoma and hypofunctional nodular goiter - a case report and literature review
title_short Synchronous cervical sympathetic chain schwannoma, parathyroid adenoma and hypofunctional nodular goiter - a case report and literature review
title_sort synchronous cervical sympathetic chain schwannoma parathyroid adenoma and hypofunctional nodular goiter a case report and literature review
topic parapharyngeal space tumor
carotid body tumor
paraganglioma
cervical sympathetic chain schwannoma
horner`s syndrome
vagal schwannoma
url https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1432&context=jmms
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