Cerium oxide nanoparticles attenuates fibrosis and inflammation in thyroid-associated ophthalmopathy via JNK pathway

Cerium oxide nanoparticles attenuates fibrosis and inflammation in thyroid-associated ophthalmopathy via JNK pathway

ObjectiveThyroid-associated ophthalmopathy (TAO) is an autoimmune orbital disorder characterized by pathological alterations including extraocular muscle fibrosis and orbital inflammation. Cerium oxide nanoparticles (CeO2-NPs, CNPs) are gaining popularity in ophthalmology due to their potential anti...

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Bibliographic Details
Main Authors:	Bo-Wen Wang, Ru Zhu, Ying Jin, Xuan Ouyang, Fa-Gang Jiang, Xing-Hua Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Molecular Biosciences
Subjects:	thyroid-associated ophthalmopathy cerium oxide nanoparticles orbital fibroblasts JNK phosphorylation fibrosis inflammation
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2025.1580062/full
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