Smoking cessation improves health status of patients with chronic diseases: evidence from a longitudinal study of older adults in China

Abstract Background Smoking is a well-documented risk factor for numerous chronic diseases, and cessation is correlated with enhanced health outcomes. Nonetheless, the precise effects of smoking cessation on the health status of older adults with chronic conditions in China have not been thoroughly...

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Main Authors: Haoyu Zhu, Peng Xu, Yumeng Wei, Chuchen Zhao, Danni Zhao, Yaxin Li, Xiaobin Ma, Meng Wang, Huafeng Kang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Public Health
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Online Access:https://doi.org/10.1186/s12889-025-22203-7
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author Haoyu Zhu
Peng Xu
Yumeng Wei
Chuchen Zhao
Danni Zhao
Yaxin Li
Xiaobin Ma
Meng Wang
Huafeng Kang
author_facet Haoyu Zhu
Peng Xu
Yumeng Wei
Chuchen Zhao
Danni Zhao
Yaxin Li
Xiaobin Ma
Meng Wang
Huafeng Kang
author_sort Haoyu Zhu
collection DOAJ
description Abstract Background Smoking is a well-documented risk factor for numerous chronic diseases, and cessation is correlated with enhanced health outcomes. Nonetheless, the precise effects of smoking cessation on the health status of older adults with chronic conditions in China have not been thoroughly quantified. Objective This study aims to quantitatively assess the correlations between smoking cessation and enhancements in the health outcomes of elderly Chinese individuals with chronic diseases. Method This research drew upon data from the China Health and Retirement Longitudinal Study (CHARLS). A cohort of 9914 participants was ultimately included in our analysis. Group comparisons and linear regression analyses were utilized. The investigation delved into health status scores, hematological markers, and physiological parameters. Result With each additional year of smoking cessation, former smokers demonstrated improved self-rated health and reduced EQ-5D-3L scores. Regression analysis unveiled a positive correlation between smoking cessation and enhanced self-assessed health (β estimate = 0.198), while a notable adverse effect was observed in EQ-5D-3L scores (β estimate = -0.179) and grip strength (β estimate = -2.530). Blood biomarkers also displayed noteworthy relationships with smoking cessation, showcasing rehabilitation in LDL cholesterol, total cholesterol, glucose, cystatin C, creatinine, HbA1c, and uric acid levels. Conclusion This research provides evidence highlighting the favorable health ramifications associated with smoking cessation in elderly individuals with chronic illnesses. Noteworthy improvements in both subjective health assessments and blood-based markers were observed post-smoking cessation, with benefits becoming more prominent with prolonged abstinence. These results underscore the vital importance of smoking cessation in the holistic care of chronic conditions and broader health enhancement endeavors. Further validation of these findings through an extended follow-up period is anticipated to bolster these conclusions with increased confidence.
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spelling doaj-art-7dfd13e798454b2aa45ff5b5118e6e9a2025-08-20T03:01:24ZengBMCBMC Public Health1471-24582025-03-0125111210.1186/s12889-025-22203-7Smoking cessation improves health status of patients with chronic diseases: evidence from a longitudinal study of older adults in ChinaHaoyu Zhu0Peng Xu1Yumeng Wei2Chuchen Zhao3Danni Zhao4Yaxin Li5Xiaobin Ma6Meng Wang7Huafeng Kang8The Comprehensive Breast Care Center, The Second Affiliated Hospital of Xi’an Jiaotong UniversityThe Comprehensive Breast Care Center, The Second Affiliated Hospital of Xi’an Jiaotong UniversityThe Comprehensive Breast Care Center, The Second Affiliated Hospital of Xi’an Jiaotong UniversityThe Comprehensive Breast Care Center, The Second Affiliated Hospital of Xi’an Jiaotong UniversityThe Comprehensive Breast Care Center, The Second Affiliated Hospital of Xi’an Jiaotong UniversityThe Comprehensive Breast Care Center, The Second Affiliated Hospital of Xi’an Jiaotong UniversityThe Comprehensive Breast Care Center, The Second Affiliated Hospital of Xi’an Jiaotong UniversityThe Comprehensive Breast Care Center, The Second Affiliated Hospital of Xi’an Jiaotong UniversityThe Comprehensive Breast Care Center, The Second Affiliated Hospital of Xi’an Jiaotong UniversityAbstract Background Smoking is a well-documented risk factor for numerous chronic diseases, and cessation is correlated with enhanced health outcomes. Nonetheless, the precise effects of smoking cessation on the health status of older adults with chronic conditions in China have not been thoroughly quantified. Objective This study aims to quantitatively assess the correlations between smoking cessation and enhancements in the health outcomes of elderly Chinese individuals with chronic diseases. Method This research drew upon data from the China Health and Retirement Longitudinal Study (CHARLS). A cohort of 9914 participants was ultimately included in our analysis. Group comparisons and linear regression analyses were utilized. The investigation delved into health status scores, hematological markers, and physiological parameters. Result With each additional year of smoking cessation, former smokers demonstrated improved self-rated health and reduced EQ-5D-3L scores. Regression analysis unveiled a positive correlation between smoking cessation and enhanced self-assessed health (β estimate = 0.198), while a notable adverse effect was observed in EQ-5D-3L scores (β estimate = -0.179) and grip strength (β estimate = -2.530). Blood biomarkers also displayed noteworthy relationships with smoking cessation, showcasing rehabilitation in LDL cholesterol, total cholesterol, glucose, cystatin C, creatinine, HbA1c, and uric acid levels. Conclusion This research provides evidence highlighting the favorable health ramifications associated with smoking cessation in elderly individuals with chronic illnesses. Noteworthy improvements in both subjective health assessments and blood-based markers were observed post-smoking cessation, with benefits becoming more prominent with prolonged abstinence. These results underscore the vital importance of smoking cessation in the holistic care of chronic conditions and broader health enhancement endeavors. Further validation of these findings through an extended follow-up period is anticipated to bolster these conclusions with increased confidence.https://doi.org/10.1186/s12889-025-22203-7Smoking cessationHealth statusCHARLSOlder adults
spellingShingle Haoyu Zhu
Peng Xu
Yumeng Wei
Chuchen Zhao
Danni Zhao
Yaxin Li
Xiaobin Ma
Meng Wang
Huafeng Kang
Smoking cessation improves health status of patients with chronic diseases: evidence from a longitudinal study of older adults in China
BMC Public Health
Smoking cessation
Health status
CHARLS
Older adults
title Smoking cessation improves health status of patients with chronic diseases: evidence from a longitudinal study of older adults in China
title_full Smoking cessation improves health status of patients with chronic diseases: evidence from a longitudinal study of older adults in China
title_fullStr Smoking cessation improves health status of patients with chronic diseases: evidence from a longitudinal study of older adults in China
title_full_unstemmed Smoking cessation improves health status of patients with chronic diseases: evidence from a longitudinal study of older adults in China
title_short Smoking cessation improves health status of patients with chronic diseases: evidence from a longitudinal study of older adults in China
title_sort smoking cessation improves health status of patients with chronic diseases evidence from a longitudinal study of older adults in china
topic Smoking cessation
Health status
CHARLS
Older adults
url https://doi.org/10.1186/s12889-025-22203-7
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