Dynamics of SERPINA3 in response to anthracycline treatment and cardiovascular dysfunction

Dynamics of SERPINA3 in response to anthracycline treatment and cardiovascular dysfunction

Abstract Background SERPINA3 recently emerged as potential prognostic biomarker in heart failure. In a population of cancer survivors with cancer therapy-related cardiac dysfunction (CTRCD) circulating SERPINA3 was elevated compared to age-matched controls. We aimed to assess the longitudinal dynami...

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Main Authors:	Hanne M. Boen, Lobke L. Pype, Konstantinos Papadimitriou, Sevilay Altintas, Laure-Anne Teuwen, Sébastien Anguille, Kirsten Saevels, Anke Verlinden, Leen Delrue, Ward A. Heggermont, Matthias Bosman, Pieter-Jan Guns, Hein Heidbuchel, Caroline M. Van De Heyning, Emeline M. Van Craenenbroeck, Constantijn Franssen
Format:	Article
Language:	English
Published:	BMC 2025-03-01
Series:	Cardio-Oncology
Subjects:	Cancer therapy-related cardiac dysfunction (CTRCD) SERPINA3 Cardiotoxicity Biomarker Anthracycline Breast cancer
Online Access:	https://doi.org/10.1186/s40959-025-00324-7
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