T-cell receptor binding prediction: A machine learning revolution

T-cell receptor binding prediction: A machine learning revolution

Recent advancements in immune sequencing and experimental techniques are generating extensive T cell receptor (TCR) repertoire data, enabling the development of models to predict TCR binding specificity. Despite the computational challenges posed by the vast diversity of TCRs and epitopes, significa...

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Bibliographic Details
Main Authors: Anna Weber, Aurélien Pélissier, María Rodríguez Martínez
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:ImmunoInformatics
Subjects:
Machine learning
T cell receptor
Specificity prediction
Protein language models
Interpretability
Online Access:http://www.sciencedirect.com/science/article/pii/S2667119024000107
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