ISG-15, beyond its functions in the cell: a mini review

ISG-15, beyond its functions in the cell: a mini review

Abstract Interferon-stimulated gene 15 (ISG15) is an interferon-stimulated gene and a ubiquitin-like protein, traditionally known for its role in ISGylation. In addition to its intracellular functions, recent studies have revealed a novel role for extracellular ISG15, particularly in the context of...

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Bibliographic Details
Main Authors: Mudassir S. Ali, Yun Sang Tang, Horace Hok Yeung Lee, Susan C. Baker, Chris Ka Pun Mok
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Cellular and Molecular Life Sciences
Subjects:
ISG-15
Extracellular
Interferon
LFA-1
Innate immunity
Online Access:https://doi.org/10.1007/s00018-025-05705-w
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