Associated minerals in chrysotile deposits and their potential health risks

Chrysotile samples from different deposits and the UICC-A and UICC-B standards have been analyzed by a procedure in which the chrysotile is removed by successive treatments in hydrochloric acid and sodium hydroxide, followed by transmission electron microscopy (TEM) examination of the residues. Two...

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Main Author: Eric J. Chatfield
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Public Health
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Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1583469/full
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author Eric J. Chatfield
author_facet Eric J. Chatfield
author_sort Eric J. Chatfield
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description Chrysotile samples from different deposits and the UICC-A and UICC-B standards have been analyzed by a procedure in which the chrysotile is removed by successive treatments in hydrochloric acid and sodium hydroxide, followed by transmission electron microscopy (TEM) examination of the residues. Two separate TEM fiber counts of a minimum of 100 fibers each were made for each sample: fibers longer than 5 μm and fibers with lengths between 0.5 μm and 5 μm. The tremolite/actinolite in each sample was quantified in terms of fibers/gram of chrysotile and as mass fraction in parts per million (ppm). Chrysotile from almost all of the commercial deposits examined was found to contain tremolite/actinolite. In particular, UICC-B Canadian chrysotile was found to contain an average of approximately 180 ppm tremolite/actinolite, equivalent to 1.25 × 107 fibers per gram (longer than 5 μm) of tremolite/actinolite, a proportion of which is asbestiform. The results also showed that both the UICC-B and UICC-A chrysotile standards are contaminated by Amosite. The primary grades of chrysotile from Coalinga, United States, and Minaçu, Brazil, were found to contain substantially less than 1 ppm of tremolite/actinolite. An asbestiform variety of the pyroxene diopside was detected in chrysotile from the Balangero mine in Italy. The asbestiform diopside has a fiber concentration and mass fraction comparable to those of tremolite/actinolite in chrysotile from other sources. Some of the diopside fibers are considerably longer than the tremolite/actinolite fibers found in other sources of chrysotile. Low levels (<4 ppm) of tremolite/actinolite were detected in Balangero chrysotile. No fibers with compositions consistent with Balangeroite were detected. It was found that Balangeroite does not survive the acid-alkali dissolution procedure, and it probably has durability comparable to that of chrysotile. Publications that claim the absence of tremolite/actinolite in UICC-B chrysotile were based on analytical methods that had insufficient sensitivity. Use of these analytical methods permitted only a 1 in 5 chance that a single tremolite/actinolite fiber would be detected. The concentrations of tremolite/actinolite and Amosite found in the reference UICC chrysotile standards raise questions as to the validity of historical biological experiments carried out using these materials.
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spelling doaj-art-7de298a52e8b4b94887e8c3b71c0f6592025-08-20T02:14:01ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-05-011310.3389/fpubh.2025.15834691583469Associated minerals in chrysotile deposits and their potential health risksEric J. ChatfieldChrysotile samples from different deposits and the UICC-A and UICC-B standards have been analyzed by a procedure in which the chrysotile is removed by successive treatments in hydrochloric acid and sodium hydroxide, followed by transmission electron microscopy (TEM) examination of the residues. Two separate TEM fiber counts of a minimum of 100 fibers each were made for each sample: fibers longer than 5 μm and fibers with lengths between 0.5 μm and 5 μm. The tremolite/actinolite in each sample was quantified in terms of fibers/gram of chrysotile and as mass fraction in parts per million (ppm). Chrysotile from almost all of the commercial deposits examined was found to contain tremolite/actinolite. In particular, UICC-B Canadian chrysotile was found to contain an average of approximately 180 ppm tremolite/actinolite, equivalent to 1.25 × 107 fibers per gram (longer than 5 μm) of tremolite/actinolite, a proportion of which is asbestiform. The results also showed that both the UICC-B and UICC-A chrysotile standards are contaminated by Amosite. The primary grades of chrysotile from Coalinga, United States, and Minaçu, Brazil, were found to contain substantially less than 1 ppm of tremolite/actinolite. An asbestiform variety of the pyroxene diopside was detected in chrysotile from the Balangero mine in Italy. The asbestiform diopside has a fiber concentration and mass fraction comparable to those of tremolite/actinolite in chrysotile from other sources. Some of the diopside fibers are considerably longer than the tremolite/actinolite fibers found in other sources of chrysotile. Low levels (<4 ppm) of tremolite/actinolite were detected in Balangero chrysotile. No fibers with compositions consistent with Balangeroite were detected. It was found that Balangeroite does not survive the acid-alkali dissolution procedure, and it probably has durability comparable to that of chrysotile. Publications that claim the absence of tremolite/actinolite in UICC-B chrysotile were based on analytical methods that had insufficient sensitivity. Use of these analytical methods permitted only a 1 in 5 chance that a single tremolite/actinolite fiber would be detected. The concentrations of tremolite/actinolite and Amosite found in the reference UICC chrysotile standards raise questions as to the validity of historical biological experiments carried out using these materials.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1583469/fullchrysotileUICCtremoliteactinolitebalangeroitediopside
spellingShingle Eric J. Chatfield
Associated minerals in chrysotile deposits and their potential health risks
Frontiers in Public Health
chrysotile
UICC
tremolite
actinolite
balangeroite
diopside
title Associated minerals in chrysotile deposits and their potential health risks
title_full Associated minerals in chrysotile deposits and their potential health risks
title_fullStr Associated minerals in chrysotile deposits and their potential health risks
title_full_unstemmed Associated minerals in chrysotile deposits and their potential health risks
title_short Associated minerals in chrysotile deposits and their potential health risks
title_sort associated minerals in chrysotile deposits and their potential health risks
topic chrysotile
UICC
tremolite
actinolite
balangeroite
diopside
url https://www.frontiersin.org/articles/10.3389/fpubh.2025.1583469/full
work_keys_str_mv AT ericjchatfield associatedmineralsinchrysotiledepositsandtheirpotentialhealthrisks