Study of raw material of alfalfa yellow (like-sickle or Romanian)

Along with the wide distribution and use of alfalfa grass there is no comprehensive scientific pharmacognosy studies about representatives of the plants of this kind. Aim. To study the content of the group of true coumarins and 4-oxyderivatives which presence must be characteristic for the yellow...

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Main Authors: O. V. Grechana, S. D. Trzhetsinskiy
Format: Article
Language:English
Published: Zaporizhzhia State Medical and Pharmaceutical University 2016-08-01
Series:Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
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Online Access:http://pharmed.zsmu.edu.ua/article/view/70696/67978
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author O. V. Grechana
S. D. Trzhetsinskiy
author_facet O. V. Grechana
S. D. Trzhetsinskiy
author_sort O. V. Grechana
collection DOAJ
description Along with the wide distribution and use of alfalfa grass there is no comprehensive scientific pharmacognosy studies about representatives of the plants of this kind. Aim. To study the content of the group of true coumarins and 4-oxyderivatives which presence must be characteristic for the yellow alfalfa. Materials and methods. The determination of diagnostic anatomical features of the plant Medicago falcata L. subsp. romanica (Prodan) O. Schwarz & Klink has been carried out. The leaf petiole has such diagnostic characteristics: elongated epidermal cells, parenchymal or prosenchymal, 4-, or (rarely) 5-6 gonal; pubescence is of simple single-celled hairs with warty cuticle, which can be found on the upper and lower epidermis of the leaf. The stomatas are rare. The rosette is formed from basal epithelial cells near the base of the hairs. Results. 66 Components have been revealed by chromatography of native raw, 38 of components have been identified, namely - dihydrocoumarin (1.60%) and coumarin (13.13%). After the acid hydrolysis 52 components have been revealed, 41 of which have been identified. These substances are the complex of biologically active compounds: primary alcohols, aldehydes, ketones. 4-Oxycumarin derivatives have been identified: coumarin - 79.38% dihydrocoumarin - 4.95%, and 6-methylcoumarin - 0.39%. While studying the amino acid composition of the above-ground parts of alfalfa yellow we got interested in a significant amount of aspartic acid, proline and phenylalanine.
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spelling doaj-art-7de1e65d11cd489588a71461b1597cd02025-08-20T03:14:54ZengZaporizhzhia State Medical and Pharmaceutical UniversityAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki2306-80942409-29322016-08-012525610.14739/2409-2932.2016.2.70696Study of raw material of alfalfa yellow (like-sickle or Romanian)O. V. GrechanaS. D. TrzhetsinskiyAlong with the wide distribution and use of alfalfa grass there is no comprehensive scientific pharmacognosy studies about representatives of the plants of this kind. Aim. To study the content of the group of true coumarins and 4-oxyderivatives which presence must be characteristic for the yellow alfalfa. Materials and methods. The determination of diagnostic anatomical features of the plant Medicago falcata L. subsp. romanica (Prodan) O. Schwarz & Klink has been carried out. The leaf petiole has such diagnostic characteristics: elongated epidermal cells, parenchymal or prosenchymal, 4-, or (rarely) 5-6 gonal; pubescence is of simple single-celled hairs with warty cuticle, which can be found on the upper and lower epidermis of the leaf. The stomatas are rare. The rosette is formed from basal epithelial cells near the base of the hairs. Results. 66 Components have been revealed by chromatography of native raw, 38 of components have been identified, namely - dihydrocoumarin (1.60%) and coumarin (13.13%). After the acid hydrolysis 52 components have been revealed, 41 of which have been identified. These substances are the complex of biologically active compounds: primary alcohols, aldehydes, ketones. 4-Oxycumarin derivatives have been identified: coumarin - 79.38% dihydrocoumarin - 4.95%, and 6-methylcoumarin - 0.39%. While studying the amino acid composition of the above-ground parts of alfalfa yellow we got interested in a significant amount of aspartic acid, proline and phenylalanine.http://pharmed.zsmu.edu.ua/article/view/70696/67978СoumarinsАmino АcidFabaceae
spellingShingle O. V. Grechana
S. D. Trzhetsinskiy
Study of raw material of alfalfa yellow (like-sickle or Romanian)
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
Сoumarins
Аmino Аcid
Fabaceae
title Study of raw material of alfalfa yellow (like-sickle or Romanian)
title_full Study of raw material of alfalfa yellow (like-sickle or Romanian)
title_fullStr Study of raw material of alfalfa yellow (like-sickle or Romanian)
title_full_unstemmed Study of raw material of alfalfa yellow (like-sickle or Romanian)
title_short Study of raw material of alfalfa yellow (like-sickle or Romanian)
title_sort study of raw material of alfalfa yellow like sickle or romanian
topic Сoumarins
Аmino Аcid
Fabaceae
url http://pharmed.zsmu.edu.ua/article/view/70696/67978
work_keys_str_mv AT ovgrechana studyofrawmaterialofalfalfayellowlikesickleorromanian
AT sdtrzhetsinskiy studyofrawmaterialofalfalfayellowlikesickleorromanian