Looking at a baby's heart through the lens of the mother's blood

Abstract Congenital heart disease (CHD) comprises several cardiovascular abnormalities existing from birth. Cardiac defects range from minor asymptomatic lesions to potentially life‐threatening situations. Early fetal echocardiography, the gold standard for the in‐utero diagnosis of CHD, is inaccura...

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Main Author: Paolo Madeddu
Format: Article
Language:English
Published: Springer Nature 2023-10-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.202318680
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author Paolo Madeddu
author_facet Paolo Madeddu
author_sort Paolo Madeddu
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description Abstract Congenital heart disease (CHD) comprises several cardiovascular abnormalities existing from birth. Cardiac defects range from minor asymptomatic lesions to potentially life‐threatening situations. Early fetal echocardiography, the gold standard for the in‐utero diagnosis of CHD, is inaccurate at identifying defects in pulmonary veins and atrioventricular valves or lesions that occur later or progress during pregnancy. In this issue of EMBO Molecular Medicine, Yin et al report new proteomic data on maternal blood samples and a novel bioinformatic and artificial intelligence approach for the early diagnosis and screening of CHD.
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spelling doaj-art-7dddf81d96374ecda2c9294a30c6dc2b2025-08-20T04:03:01ZengSpringer NatureEMBO Molecular Medicine1757-46761757-46842023-10-0115121310.15252/emmm.202318680Looking at a baby's heart through the lens of the mother's bloodPaolo Madeddu0Bristol Medical School, Translational Health Sciences, and Bristol Heart Institute, University of BristolAbstract Congenital heart disease (CHD) comprises several cardiovascular abnormalities existing from birth. Cardiac defects range from minor asymptomatic lesions to potentially life‐threatening situations. Early fetal echocardiography, the gold standard for the in‐utero diagnosis of CHD, is inaccurate at identifying defects in pulmonary veins and atrioventricular valves or lesions that occur later or progress during pregnancy. In this issue of EMBO Molecular Medicine, Yin et al report new proteomic data on maternal blood samples and a novel bioinformatic and artificial intelligence approach for the early diagnosis and screening of CHD.https://doi.org/10.15252/emmm.202318680
spellingShingle Paolo Madeddu
Looking at a baby's heart through the lens of the mother's blood
EMBO Molecular Medicine
title Looking at a baby's heart through the lens of the mother's blood
title_full Looking at a baby's heart through the lens of the mother's blood
title_fullStr Looking at a baby's heart through the lens of the mother's blood
title_full_unstemmed Looking at a baby's heart through the lens of the mother's blood
title_short Looking at a baby's heart through the lens of the mother's blood
title_sort looking at a baby s heart through the lens of the mother s blood
url https://doi.org/10.15252/emmm.202318680
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