Looking at a baby's heart through the lens of the mother's blood

Abstract Congenital heart disease (CHD) comprises several cardiovascular abnormalities existing from birth. Cardiac defects range from minor asymptomatic lesions to potentially life‐threatening situations. Early fetal echocardiography, the gold standard for the in‐utero diagnosis of CHD, is inaccura...

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Bibliographic Details
Main Author: Paolo Madeddu
Format: Article
Language:English
Published: Springer Nature 2023-10-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.202318680
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Summary:Abstract Congenital heart disease (CHD) comprises several cardiovascular abnormalities existing from birth. Cardiac defects range from minor asymptomatic lesions to potentially life‐threatening situations. Early fetal echocardiography, the gold standard for the in‐utero diagnosis of CHD, is inaccurate at identifying defects in pulmonary veins and atrioventricular valves or lesions that occur later or progress during pregnancy. In this issue of EMBO Molecular Medicine, Yin et al report new proteomic data on maternal blood samples and a novel bioinformatic and artificial intelligence approach for the early diagnosis and screening of CHD.
ISSN:1757-4676
1757-4684