A genetically engineered therapeutic lectin inhibits human influenza A virus infection and sustains robust virus-specific CD8 T cell expansion.
Seasonal influenza continues to be a global health problem. Current existing vaccines and antivirals against influenza have limited effectiveness, and typically do not stay ahead of the viral evolutionary curve. Broad-spectrum antiviral agents that are effective therapeutically and prophylactically...
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| Main Authors: | Meng Yu, Ang Lin, Faezzah Baharom, Shuijie Li, Maureen Legendre, Evelyn Covés-Datson, Ebba Sohlberg, Susanne Schlisio, Karin Loré, David M Markovitz, Anna Smed-Sörensen |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-05-01
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| Series: | PLoS Pathogens |
| Online Access: | https://doi.org/10.1371/journal.ppat.1013112 |
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