Circulating CCN6/WISP3 in type 2 diabetes mellitus patients and its correlation with insulin resistance and inflammation: statistical and machine learning analyses

Circulating CCN6/WISP3 in type 2 diabetes mellitus patients and its correlation with insulin resistance and inflammation: statistical and machine learning analyses

Abstract Introduction Cellular Communication Network Factor 6 (CCN6) is an adipokine whose production undergoes significant alterations in metabolic disorders. Given the well-established link between obesity-induced adipokine dysfunction and the development of insulin resistance and type 2 diabetes...

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Main Authors: Reza Afrisham, Yasaman Jadidi, Nariman Moradi, Seyed Mohammad Ayyoubzadeh, Reza Fadaei, Omid Kiani Ghalesardi, Vida Farrokhi, Shaban Alizadeh
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Medical Informatics and Decision Making
Subjects:
WISP3/CCN6
Type 2 diabetes mellitus
Inflammatory cytokines
Insulin resistance
Adiponectin
Online Access:https://doi.org/10.1186/s12911-025-02957-1
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