Dietary bisphenols exposure as an influencing factor of body mass index
Abstract Background Over the past three decades, there has been a significant increase in the prevalence and incidence of overweight and obesity worldwide. The obesogen hypothesis suggests that certain external agents may affect pathways related to fat accumulation and energy balance by stimulating...
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BMC
2024-10-01
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| Series: | Environmental Health |
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| Online Access: | https://doi.org/10.1186/s12940-024-01134-7 |
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| author | Yolanda Gálvez-Ontiveros Celia Monteagudo María Giles-Mancilla José Joaquín Muros Vega Almazán María Alba Martínez-Burgos Cristina Samaniego-Sánchez Inmaculada Salcedo-Bellido Ana Rivas Alberto Zafra-Gómez |
| author_facet | Yolanda Gálvez-Ontiveros Celia Monteagudo María Giles-Mancilla José Joaquín Muros Vega Almazán María Alba Martínez-Burgos Cristina Samaniego-Sánchez Inmaculada Salcedo-Bellido Ana Rivas Alberto Zafra-Gómez |
| author_sort | Yolanda Gálvez-Ontiveros |
| collection | DOAJ |
| description | Abstract Background Over the past three decades, there has been a significant increase in the prevalence and incidence of overweight and obesity worldwide. The obesogen hypothesis suggests that certain external agents may affect pathways related to fat accumulation and energy balance by stimulating fat cell differentiation and proliferation. Previous research has indicated that exposure to bisphenol A (BPA) and some of its analogues may influence fat accumulation by promoting the transformation of preadipocytes into adipocytes. This study aimed to assess the possible contribution of dietary bisphenol exposure to the odds of developing overweight and obesity in a sample of Spanish children according to sex. Methods Dietary and anthropometric data were collected from 179 controls and 124 cases schoolchildren aged 3–12 years. Dietary exposure to BPA and bisphenol S (BPS) was assessed using a food consumption frequency questionnaire. Logistic regression models were used to assess the influence of dietary exposure to bisphenols on overweight and obesity stratified by sex. Results For females, cases had significantly higher exposure to BPA from meat and eggs compared to controls (median = 319.55, interquartile range (IQR) = 176.39–381.01 vs 231.79 (IQR) = 162.11–350.19, p-value = 0.046). Diet quality was higher for controls (6.21 (2.14) vs 4.80 (2.24) p < 0.001) among males independently of a high or low exposure to bisphenols. However, higher diet quality was observed for female controls with an high exposure of total bisphenols (6.79 (2.04) vs 5.33 (2.02) p = 0.031). Females exposed to high levels of BPA from meat and eggs had higher likelihood of being overweight and obese (adjusted Odds Ratio = 2.70, 95% confidence interval = 1.00 – 7.32). However, no consistent associations were found in males. Conclusions High BPA levels from meat and eggs were positively associated with overweight and obesity in females. The dietary intake of BPA in the schoolchildren in the present study was much higher than the acceptable daily intake established by EFSA for the last year. |
| format | Article |
| id | doaj-art-7dd491f174e647ff86b8b0198f6792ce |
| institution | OA Journals |
| issn | 1476-069X |
| language | English |
| publishDate | 2024-10-01 |
| publisher | BMC |
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| series | Environmental Health |
| spelling | doaj-art-7dd491f174e647ff86b8b0198f6792ce2025-08-20T02:18:28ZengBMCEnvironmental Health1476-069X2024-10-0123111310.1186/s12940-024-01134-7Dietary bisphenols exposure as an influencing factor of body mass indexYolanda Gálvez-Ontiveros0Celia Monteagudo1María Giles-Mancilla2José Joaquín Muros3Vega Almazán4María Alba Martínez-Burgos5Cristina Samaniego-Sánchez6Inmaculada Salcedo-Bellido7Ana Rivas8Alberto Zafra-Gómez9Department of Nutrition and Food Science, University of GranadaDepartment of Nutrition and Food Science, University of GranadaDepartment of Nutrition and Food Science, University of GranadaDepartment of Didactics and Corporal Expression, University of GranadaMaracena Health Center, Andalusian Health Service“José Mataix Verdú” Institute of Nutrition and Food Technology (INYTA), Biomedical Research Centre (CIBM), University of GranadaDepartment of Nutrition and Food Science, University of GranadaInstituto de Investigación Biosanitaria Ibs. GRANADADepartment of Nutrition and Food Science, University of GranadaInstituto de Investigación Biosanitaria Ibs. GRANADAAbstract Background Over the past three decades, there has been a significant increase in the prevalence and incidence of overweight and obesity worldwide. The obesogen hypothesis suggests that certain external agents may affect pathways related to fat accumulation and energy balance by stimulating fat cell differentiation and proliferation. Previous research has indicated that exposure to bisphenol A (BPA) and some of its analogues may influence fat accumulation by promoting the transformation of preadipocytes into adipocytes. This study aimed to assess the possible contribution of dietary bisphenol exposure to the odds of developing overweight and obesity in a sample of Spanish children according to sex. Methods Dietary and anthropometric data were collected from 179 controls and 124 cases schoolchildren aged 3–12 years. Dietary exposure to BPA and bisphenol S (BPS) was assessed using a food consumption frequency questionnaire. Logistic regression models were used to assess the influence of dietary exposure to bisphenols on overweight and obesity stratified by sex. Results For females, cases had significantly higher exposure to BPA from meat and eggs compared to controls (median = 319.55, interquartile range (IQR) = 176.39–381.01 vs 231.79 (IQR) = 162.11–350.19, p-value = 0.046). Diet quality was higher for controls (6.21 (2.14) vs 4.80 (2.24) p < 0.001) among males independently of a high or low exposure to bisphenols. However, higher diet quality was observed for female controls with an high exposure of total bisphenols (6.79 (2.04) vs 5.33 (2.02) p = 0.031). Females exposed to high levels of BPA from meat and eggs had higher likelihood of being overweight and obese (adjusted Odds Ratio = 2.70, 95% confidence interval = 1.00 – 7.32). However, no consistent associations were found in males. Conclusions High BPA levels from meat and eggs were positively associated with overweight and obesity in females. The dietary intake of BPA in the schoolchildren in the present study was much higher than the acceptable daily intake established by EFSA for the last year.https://doi.org/10.1186/s12940-024-01134-7ChildrenOverweightObesityBisphenol ABisphenol SWeight excess |
| spellingShingle | Yolanda Gálvez-Ontiveros Celia Monteagudo María Giles-Mancilla José Joaquín Muros Vega Almazán María Alba Martínez-Burgos Cristina Samaniego-Sánchez Inmaculada Salcedo-Bellido Ana Rivas Alberto Zafra-Gómez Dietary bisphenols exposure as an influencing factor of body mass index Environmental Health Children Overweight Obesity Bisphenol A Bisphenol S Weight excess |
| title | Dietary bisphenols exposure as an influencing factor of body mass index |
| title_full | Dietary bisphenols exposure as an influencing factor of body mass index |
| title_fullStr | Dietary bisphenols exposure as an influencing factor of body mass index |
| title_full_unstemmed | Dietary bisphenols exposure as an influencing factor of body mass index |
| title_short | Dietary bisphenols exposure as an influencing factor of body mass index |
| title_sort | dietary bisphenols exposure as an influencing factor of body mass index |
| topic | Children Overweight Obesity Bisphenol A Bisphenol S Weight excess |
| url | https://doi.org/10.1186/s12940-024-01134-7 |
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