Cardiac fibroblasts regulate myocardium and coronary vasculature development in the murine heart via the collagen signaling pathway

Cardiac fibroblasts regulate myocardium and coronary vasculature development in the murine heart via the collagen signaling pathway

The fibroblast (FB), cardiomyocyte (CM), and vascular endothelial cell (Vas_EC) are the three major cell types in the heart, yet their relationships during development are largely unexplored. To address this gap, we employed RNA staining of the FB marker gene Col1a1 together with the CM marker gene...

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Bibliographic Details
Main Authors: Yiting Deng, Yuanhang He, Juan Xu, Haoting He, Manling Zhang, Guang Li
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-07-01
Series:eLife
Subjects:
fibroblast
extracellular matrix
ablation
heart
single cell
myocardium
Online Access:https://elifesciences.org/articles/102305
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