Tears of The Retinal Pigment Epithelium – A Review
Tears of the retinal pigment epithelium (RPE) may occur in eyes with a large pigment epithelial detachment (PED). They are most commonly associated with vascularized RPE detachment due to age-related macular degeneration (AMD) and usually involve a deleterious loss in visual acuity. With the extensi...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-10-01
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| Series: | Delhi Journal of Ophthalmology |
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| Online Access: | https://journals.lww.com/10.7869/djo.258 |
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| author | Anika Gupta Mohit Chhabra Parth Mehta Basudeb Ghosh |
| author_facet | Anika Gupta Mohit Chhabra Parth Mehta Basudeb Ghosh |
| author_sort | Anika Gupta |
| collection | DOAJ |
| description | Tears of the retinal pigment epithelium (RPE) may occur in eyes with a large pigment epithelial detachment (PED). They are most commonly associated with vascularized RPE detachment due to age-related macular degeneration (AMD) and usually involve a deleterious loss in visual acuity. With the extensive use of anti-vascular endothelial growth factor (anti-VEGF) therapy for treatment of eyes with neovascular AMD, recently there has been an increase in the incidence of RPE tear. Multimodal retinal imaging techniques help in accurate detection of RPE tears and help in identifying eyes with high risk factors for RPE tears formation. Understanding the pathogenesis and risk factors of RPE tears is important for better management of these eyes as RPE tears are associated with poor visual prognosis, especially if the fovea is involved. This review summarizes the current knowledge on RPE tear pathogenesis, risk factors for an impending tear, and approach to management of these eyes before and after RPE tear formation |
| format | Article |
| id | doaj-art-7dbd656cbc5b44439b280a3fc859b61c |
| institution | DOAJ |
| issn | 0972-0200 2454-2784 |
| language | English |
| publishDate | 2017-10-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Delhi Journal of Ophthalmology |
| spelling | doaj-art-7dbd656cbc5b44439b280a3fc859b61c2025-08-20T03:11:55ZengWolters Kluwer Medknow PublicationsDelhi Journal of Ophthalmology0972-02002454-27842017-10-0127424324910.7869/djo.258Tears of The Retinal Pigment Epithelium – A ReviewAnika GuptaMohit ChhabraParth MehtaBasudeb GhoshTears of the retinal pigment epithelium (RPE) may occur in eyes with a large pigment epithelial detachment (PED). They are most commonly associated with vascularized RPE detachment due to age-related macular degeneration (AMD) and usually involve a deleterious loss in visual acuity. With the extensive use of anti-vascular endothelial growth factor (anti-VEGF) therapy for treatment of eyes with neovascular AMD, recently there has been an increase in the incidence of RPE tear. Multimodal retinal imaging techniques help in accurate detection of RPE tears and help in identifying eyes with high risk factors for RPE tears formation. Understanding the pathogenesis and risk factors of RPE tears is important for better management of these eyes as RPE tears are associated with poor visual prognosis, especially if the fovea is involved. This review summarizes the current knowledge on RPE tear pathogenesis, risk factors for an impending tear, and approach to management of these eyes before and after RPE tear formationhttps://journals.lww.com/10.7869/djo.258retinal pigment epithelial tearsretinal pigment epithelium ripneovascular age-related macular degenerationpigment epithelial detachmentcentral serous chorioretinopathyanti-vascular endothelial growth factor |
| spellingShingle | Anika Gupta Mohit Chhabra Parth Mehta Basudeb Ghosh Tears of The Retinal Pigment Epithelium – A Review Delhi Journal of Ophthalmology retinal pigment epithelial tears retinal pigment epithelium rip neovascular age-related macular degeneration pigment epithelial detachment central serous chorioretinopathy anti-vascular endothelial growth factor |
| title | Tears of The Retinal Pigment Epithelium – A Review |
| title_full | Tears of The Retinal Pigment Epithelium – A Review |
| title_fullStr | Tears of The Retinal Pigment Epithelium – A Review |
| title_full_unstemmed | Tears of The Retinal Pigment Epithelium – A Review |
| title_short | Tears of The Retinal Pigment Epithelium – A Review |
| title_sort | tears of the retinal pigment epithelium a review |
| topic | retinal pigment epithelial tears retinal pigment epithelium rip neovascular age-related macular degeneration pigment epithelial detachment central serous chorioretinopathy anti-vascular endothelial growth factor |
| url | https://journals.lww.com/10.7869/djo.258 |
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