Increased decision thresholds enhance information gathering performance in juvenile Obsessive-Compulsive Disorder (OCD).
Patients with obsessive-compulsive disorder (OCD) can be described as cautious and hesitant, manifesting an excessive indecisiveness that hinders efficient decision making. However, excess caution in decision making may also lead to better performance in specific situations where the cost of extende...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2017-04-01
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| Series: | PLoS Computational Biology |
| Online Access: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005440&type=printable |
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| author | Tobias U Hauser Michael Moutoussis Reto Iannaccone Silvia Brem Susanne Walitza Renate Drechsler Peter Dayan Raymond J Dolan |
| author_facet | Tobias U Hauser Michael Moutoussis Reto Iannaccone Silvia Brem Susanne Walitza Renate Drechsler Peter Dayan Raymond J Dolan |
| author_sort | Tobias U Hauser |
| collection | DOAJ |
| description | Patients with obsessive-compulsive disorder (OCD) can be described as cautious and hesitant, manifesting an excessive indecisiveness that hinders efficient decision making. However, excess caution in decision making may also lead to better performance in specific situations where the cost of extended deliberation is small. We compared 16 juvenile OCD patients with 16 matched healthy controls whilst they performed a sequential information gathering task under different external cost conditions. We found that patients with OCD outperformed healthy controls, winning significantly more points. The groups also differed in the number of draws required prior to committing to a decision, but not in decision accuracy. A novel Bayesian computational model revealed that subjective sampling costs arose as a non-linear function of sampling, closely resembling an escalating urgency signal. Group difference in performance was best explained by a later emergence of these subjective costs in the OCD group, also evident in an increased decision threshold. Our findings present a novel computational model and suggest that enhanced information gathering in OCD can be accounted for by a higher decision threshold arising out of an altered perception of costs that, in some specific contexts, may be advantageous. |
| format | Article |
| id | doaj-art-7dbb7d3ba5094ec3a88a69e578dec7e3 |
| institution | DOAJ |
| issn | 1553-734X 1553-7358 |
| language | English |
| publishDate | 2017-04-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Computational Biology |
| spelling | doaj-art-7dbb7d3ba5094ec3a88a69e578dec7e32025-08-20T03:11:25ZengPublic Library of Science (PLoS)PLoS Computational Biology1553-734X1553-73582017-04-01134e100544010.1371/journal.pcbi.1005440Increased decision thresholds enhance information gathering performance in juvenile Obsessive-Compulsive Disorder (OCD).Tobias U HauserMichael MoutoussisReto IannacconeSilvia BremSusanne WalitzaRenate DrechslerPeter DayanRaymond J DolanPatients with obsessive-compulsive disorder (OCD) can be described as cautious and hesitant, manifesting an excessive indecisiveness that hinders efficient decision making. However, excess caution in decision making may also lead to better performance in specific situations where the cost of extended deliberation is small. We compared 16 juvenile OCD patients with 16 matched healthy controls whilst they performed a sequential information gathering task under different external cost conditions. We found that patients with OCD outperformed healthy controls, winning significantly more points. The groups also differed in the number of draws required prior to committing to a decision, but not in decision accuracy. A novel Bayesian computational model revealed that subjective sampling costs arose as a non-linear function of sampling, closely resembling an escalating urgency signal. Group difference in performance was best explained by a later emergence of these subjective costs in the OCD group, also evident in an increased decision threshold. Our findings present a novel computational model and suggest that enhanced information gathering in OCD can be accounted for by a higher decision threshold arising out of an altered perception of costs that, in some specific contexts, may be advantageous.https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005440&type=printable |
| spellingShingle | Tobias U Hauser Michael Moutoussis Reto Iannaccone Silvia Brem Susanne Walitza Renate Drechsler Peter Dayan Raymond J Dolan Increased decision thresholds enhance information gathering performance in juvenile Obsessive-Compulsive Disorder (OCD). PLoS Computational Biology |
| title | Increased decision thresholds enhance information gathering performance in juvenile Obsessive-Compulsive Disorder (OCD). |
| title_full | Increased decision thresholds enhance information gathering performance in juvenile Obsessive-Compulsive Disorder (OCD). |
| title_fullStr | Increased decision thresholds enhance information gathering performance in juvenile Obsessive-Compulsive Disorder (OCD). |
| title_full_unstemmed | Increased decision thresholds enhance information gathering performance in juvenile Obsessive-Compulsive Disorder (OCD). |
| title_short | Increased decision thresholds enhance information gathering performance in juvenile Obsessive-Compulsive Disorder (OCD). |
| title_sort | increased decision thresholds enhance information gathering performance in juvenile obsessive compulsive disorder ocd |
| url | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1005440&type=printable |
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