The role of inflammation resolution speed in airway smooth muscle mass accumulation in asthma: insight from a theoretical model.

The role of inflammation resolution speed in airway smooth muscle mass accumulation in asthma: insight from a theoretical model.

Despite a large amount of in vitro data, the dynamics of airway smooth muscle (ASM) mass increase in the airways of patients with asthma is not well understood. Here, we present a novel mathematical model that describes qualitatively the growth dynamics of ASM cells over short and long terms in the...

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Bibliographic Details
Main Authors: Igor L Chernyavsky, Huguette Croisier, Lloyd A C Chapman, Laura S Kimpton, Jonathan E Hiorns, Bindi S Brook, Oliver E Jensen, Charlotte K Billington, Ian P Hall, Simon R Johnson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0090162
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