Antimicrobial evaluation, molecular docking, DFT analysis, and ADME studies of 3-Hydroxypyridin-4-one analogues

Antimicrobial evaluation, molecular docking, DFT analysis, and ADME studies of 3-Hydroxypyridin-4-one analogues

A series of 3-hydroxypyridine-4-one analogues (5a–r, 6a–r) were evaluated for their antimicrobial activities against a broad panel of bacterial (E. coli, S. typhi, P. aeruginosa, B. subtilis, K. pneumoniae, and S. aureus) and fungal (C. albicans, A. niger, C. krusei, C. tropicalis, C. glabrata, C. p...

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Bibliographic Details
Main Authors: Hossein Sadeghpour, Sara Sadeghian, Fateme Zare, Mehdi Jamali, Narjes Moghtaderi Estahbanati, Kamiar Zomorodian, Zahra Zareshahrabadi, Razieh Sabet
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Results in Chemistry
Subjects:
3-Hydroxypyridine-4-one
Antimicrobial
Molecular docking
DFT analysis
And ADME studies
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625004308
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