Validation of eight endotypes of lupus based on whole-blood RNA profiles

Objective We previously described a classification system of persons with SLE based on whole blood RNA profiles and a random forest (RF) algorithm to predict individual patient endotypes. Here, we apply this algorithm prospectively in an independent set of patients to validate its use as a staging b...

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Bibliographic Details
Main Authors: Peter E Lipsky, Prathyusha Bachali, Amrie C Grammer, Erika Hubbard
Format: Article
Language:English
Published: BMJ Publishing Group 2025-05-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/12/1/e001526.full
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